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For Perimenopause

Femmenessence®

MacaLife®

$36.99 USD
$36.99 USD
Sale Out of Stock
60-Day Supply

1-Box One-Time Purchase $36.99 2-Box Subscribe & Save $59.19

Femmenessence MacaLife has the highest success rate in published clinical trials of any perimenopausal herbal supplement in the world and is the only to demonstrate statistically significant effects on hormones.* 

It works for 8 out of 10 women within 2 days to 8 weeks (the first box) with the majority within 3 weeks** and addresses the root cause of hot flashes, night sweats, mood swings and other menopausal symptoms by balancing your body’s own hormone production through the Hypothalamus. Most women see significant improvements in the first box with even greater health benefits after 3-4 months (2 boxes).

Shipping & Returns

We know how important it is to get your order quickly, so we offer a variety of shipping options to suit your needs!

For U.S. Orders:

  • Free Shipping: Enjoy free shipping on all U.S. orders over $75, as well as all Subscribe & Save orders.
  • Standard Shipping: Expect your order to arrive within 2 to 5 business days. We’ll do our best to get your order to you as quickly as possible!
  • Expedited Shipping: Need your order faster? With expedited shipping, you can expect delivery within 2 business days from the time your order is processed.

Please Note:

  • Orders placed over the weekend or on a national holiday will be processed on the next business day.
  • While we work hard to get your order out on time, please be aware that we’re not responsible for any shipping carrier delays once the package leaves our hands.

We’re here to ensure a smooth and hassle-free experience! If you have any questions about your order, feel free to reach out to us at customer.service@symphonynaturalhealth.com

Returns, Exchanges and Refund Policy

At Symphony Natural Health, our top priority is ensuring you get the results you’re looking for. If for any reason you need to return or exchange a product, we’re here to help! Please review our policy below.

Returns for Unopened, Unused Product

We want you to feel great about your order! That’s why we offer a 30-day return policy from the day you receive your order, for any order or item you need to return that is unopened, unused, and in its original packaging. Don’t forget to keep your proof of purchase handy!

Starting Your Return:
It’s easy-just reach out to us at customer.service@symphonynaturalhealth.com or give us a call at 415-243-9991. We’ll guide you step by step through the return process. Please note that we cannot accept items returned without first contacting us, so be sure to reach out!

Damaged or Incorrect Items

How annoying! We’re really sorry about this! Mistakes happen, and sometimes things go wrong during shipping, but we are here to make it right. If your item arrived damaged, defective, or if it’s not what you ordered, contact us right away at customer.service@symphonynaturalhealth.com or call 415-243-9991. We’ll make it right as quickly as possible!

Exchanges

Ordered the wrong item and want to swap for the right one? No worries! We’re happy to help with exchanges—just get in touch with us at customer.service@symphonynaturalhealth.com or call 415-243-9991, and we’ll take care of it.

Refunds for Opened or Used Products

If you’ve already opened or used your product and feel it’s not working as expected, we’re here to help! Our goal is to ensure you get the best possible results.

Our Medical Team is available 7 days a week to provide personalized support. With over 17 years of experience, we’ve found that small adjustments—like tweaking your dosage or improving hydration—can make all the difference.

Many people see great results using our products on their own, but with personalized guidance, outcomes can be even better. That’s why we’re so committed to offering this support—because when you have the right information and expert insight, you’re more likely to achieve the results you’re looking for. This level of care is what sets us apart.

And if, after following our Medical Team’s guidance, you’re still not seeing the results you hoped for, we’ll gladly issue you a full refund.

When you feel your best, you become part of the Symphony Natural Health family—and that’s what truly matters to us.

You can reach them 7 days a week at medical.team@symphonynaturalhealth.com. We’re here to help!

Refund Policy Details

  • Shipping Costs: If your order didn’t qualify for free shipping, we’ll refund the product price, but shipping costs are non-refundable and a restocking fee of $9.99 may apply.
  • Unopened and Unused Products: For returns of unopened and unused products within 30 days, simply contact our Customer Care Team at customer.service@symphonynaturalhealth.com
  • Returns Outside the 30-Day Window: These returns will be handled on a case-by-case basis, at the discretion of our Customer Care Manager.

Opened Products: Returns for opened products will be managed by our Medical Team to ensure you receive the best possible guidance on using the product.

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What is most important to you?

Your body’s changing—and asking for something deeper. It’s time to feel supported, not dismissed.

Every woman’s journey through perimenopause is unique—physically, emotionally, mentally, and spiritually. At Symphony, we recognize that your experience during this transitional phase is different from anyone else’s. Our goal is to empower you every step of the way; providing  you with the support and options you need to make the best choices for your health.

For many women, the focus may be on managing physical changes like reducing hot flashes, improving sleep, boosting energy, and supporting heart and bone health. For others, it may be about balancing mood, supporting mental clarity, and maintaining emotional well-being. And for some, this journey includes rediscovering their sense of purpose, strengthening relationships, and finding a deeper connection with their community.

Symphony isn’t just a natural products company—we’re here to support your whole self. Our Medical Team, with expertise in physical, emotional, mental, and spiritual health, is ready to guide you. Your personalized Femmenessence Journey will encompass all aspects of well-being that are important to you, from physical health to a deeper sense of purpose and community.

You are not one-dimensional, and neither is your journey. Femmenessence is here to help you thrive, not only by reclaiming your health but also by embracing every aspect of who you are, as you navigate this meaningful stage of life.

Femmenessence®: Clinically Proven to Support Women's Hormonal Health

Femmenessence MacaLife® is truly unique. It’s one of the few natural products with extensive scientific and clinical research backing it, including studies on the exact ingredient we use. These studies, including pharmacology and toxicology studies, as well as a double-blind placebo controlled human clinical trial, have all been published in respected international medical journals.

What makes Femmenessence MacaLife® so special?  It's the first natural product shown in published clinical trials to have statistically significant effects on hormones in perimenopausal women. Our own published clinical trials confirm that MacaLife reduces perimenopausal symptoms in 8 out of 10 women. This powerful impact on hormones doesn’t just address common symptoms like hot flashes and night sweats—it goes deeper, supporting heart and mental health, areas where hormones play a vital role for women going through perimenopause.

By choosing Femmenessence MacaLife, you’re supporting:

  • Normal hormone balance*
  • Hot flashes and night sweats*
  • Dryness and lack of desire*
  • Balanced mood*
  • Healthy energy levels*
  • Improved sleep*
  • Heart health*
  • Brain health*
  • Healthy body weight*
  • Hair, skin and nails*

Not only does Femmenessence work for all symptoms, but it has one of the highest success rates among natural products for reducing postmenopausal symptoms—74-82% in clinical trials.  And since those studies, we’ve seen that success rate increase to 95% when our customers receive personalized guidance from our Medical Team. By offering tailored advice on dosing, hydration and other diet and lifestyle factors, we help you get the most from Femmenessence.

What’s even more remarkable is how quickly Femmenessence works. In our clinical trials, women reported relief as fast as 2 days and up to 8 weeks, with most experiencing results in just 21 days, which is within their first box.**

But perhaps the most groundbreaking aspect of Femmenessence is how it works. Unlike other options that introduce plant or synthetic hormones into the body, Femmenessence addresses the root cause of hormonal imbalance by nourishing the Hypothalamus-Pituitary-Thyroid-Adrenal-Ovarian (HPTAO) axis. This axis is responsible for regulating the endocrine system, and supporting your body’s own hormone production, to restore your natural balance and harmony.

In our clinical trials, this approach led to positive impacts on key hormones, including:

  • Estradiol*
  • Progesterone*
  • Adrenals*

Hormonal balance plays a critical role in:

  • Relieving the symptoms of menopause*
  • Supporting foundation health as you age*
  • Turning back the biological clock*

Estradiol

As shown in these graphs, Femmenessence supports the body’s natural production of estradiol, unlike the placebo group which saw no statistically significant change. What’s especially fascinating is how Femmenessence helps the body reach an optimal estradiol level for postmenopausal women, and once this ideal level is reached, the production naturally plateaus, rather than continually increasing to levels of a young woman.

The average estradiol levels (measured in picograms per milliliter, or pg/mL) fluctuate throughout the menstrual cycle. Functional Health provides a more precise breakdown based on the different phases of the cycle, using Quest Diagnostics data:

  • Follicular Phase: 19-144 pg/mL
  • Mid-Cycle (Ovulation): 64-357 pg/mL
  • Luteal Phase: 56-214 pg/mL
  • Postmenopause: ≤ 31 pg/mL (significantly lower after menopause due to the cessation of ovarian function)

Note: There is no established pre-pubertal reference range using this assay.

Progesterone

Progesterone plays a critical role in regulating a woman’s menstrual cycle, preparing the uterus for pregnancy, and maintaining early pregnancy. As women age, progesterone production naturally declines, especially during perimenopause and menopause, leading to hormonal imbalances that can affect mood, sleep, and overall well-being.

The average levels of progesterone in women fluctuate throughout the menstrual cycle and reproductive stages. While progesterone testing is not part of Functional Health’s standard offerings, Quest Diagnostics provides the following reference ranges:

  • Follicular Phase: < 1.0 ng/mL
  • Luteal Phase: 2.6-21.5 ng/mL (peaks after ovulation as the body prepares for possible pregnancy)
  • Postmenopause: < 0.5 ng/mL (progesterone levels drop significantly after menopause due to the cessation of ovarian function)

Note: No reference ranges have been established for individuals under 18 years old using this assay.

As shown  in the graphs above, Femmenessence supports the body’s own production of Progesterone, unlike the placebo group, which saw no statistically significant positive changes. What’s particularly interesting is how Femmenessence improves Progesterone levels while not changing them to the level of a premenopausal woman. 

Scientific Gold Standards

In our clinical trials,  we used Kupperman’s Menopausal Index and Greene’s Menopausal Score, the scientific gold standards for assessing menopausal symptoms, to accurately compare Femmenessence to other products. One of the most interesting aspects of our research involved a placebo cross-over method. In this study, women began taking Femmenessence and saw a significant reduction in symptoms within two months. Then (without their knowledge), they were then switched to a placebo, and their symptoms worsened in the third month. When they unknowingly switched back to Femmenessence, their symptoms improved dramatically once again. This clearly demonstrated that Femmenessence was responsible for the significant improvements in their menopausal symptoms.

Heart Health 

Estrogen and progesterone play vital roles in heart health due to their function in the body. Estrogen helps increase HDL (the “good” cholesterol), reduce LDL (the “bad” cholesterol), and maintain the elasticity of arteries. Progesterone, often called the “relaxing hormone”,  protects arteries from spasms, especially during  a heart attack. 

In our double-blind, placebo cross-over clinical trials, Femmenessence supported healthy hormone levels, and over 3-4 months, showed the following benefits:

  • Balanced HDL, LDL and triglycerides*
  • Supported blood pressure within a normal range*
  • Supported a healthy body weight*
  • Helped maintain balanced blood sugar levels (insulin – glucagon)*

Mental Health

Hormones and neurotransmitters act as messengers within the brain and body, influencing mood, memory, and overall function. If your body struggles to produce enough of these messengers or if their pathways are disrupted, it can impact your mental health.

  • Femmenessence uniquely supports both by providing essential amino acids that are the building blocks to produce both hormones and neurotransmitters*
  • It also supports estrogen, which improves the connections and communication between neurons and cells*
  • Additionally, Femmenessence helps maintain healthy cortisol levels, reducing stress and promoting better sleep patterns.*

Hair, Skin and Nails

Our hair, skin, and nails are deeply affected by hormonal changes, especially during peri- and post-menopause. The balance of hormones like androgens (male-type hormones) and thyroid function plays a key role in maintaining hair growth and skin elasticity. When this balance is disrupted, it can lead to hair thinning, dry or sagging skin, and brittle nails. In addition, without proper iron levels, many women find it difficult to respond to hair and skin treatments.

Femmenessence works to support this delicate balance. In our clinical trials, it was shown to:

  • Support thyroid function, essential for hair and skin health*
  • Improve iron absorption, vital for hair growth and strength*
  • Balance androgen levels, which can reduce hair loss and acne*
  • Support a healthy stress response, improving overall well-being*

Many women and clinicians have reported noticeable improvements in hair retention (less shedding), clearer complexions, and stronger nails after using Femmenessence.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

How Femmenessence Works: Reframing the Menopause Journey

Menopause isn’t a single moment in time—it’s a deeply personal and evolving journey that every woman experiences differently. By choosing Femmenessence, you’re not just managing symptoms; you’re supporting your body in profound ways:

  • Natural hormone balance*
  • Hot flashes and night sweats*
  • Dryness and lack of desire*
  • Balanced mood*
  • Healthy energy levels*
  • Improved sleep*
  • Heart health*
  • Bone health*
  • Brain health*
  • Healthy body weight*
  • Hair, skin, and nails*

While conventional approaches often frame menopause as the body simply "running out" of hormones, it’s much more nuanced. The focus has historically been on hormone decline, leading to a common belief that the solution is to add hormones—through synthetic or bioidentical hormone therapy. But is introducing exogenous hormones the right path for every woman?

At Symphony, we believe menopause is not something to be "fixed" by flooding the body with hormones, but an opportunity to help your body naturally restore balance. Rather than just managing symptoms or replacing hormones, Femmenessence supports your body’s own hormone production, allowing you to adapt to this stage of life in a way that feels right for you—physically, mentally, emotionally, spiritually, and sexually.

It’s OK to Focus on Your Own Journey

As women, we evolve throughout life, and our needs during menopause are no different. Every woman’s experience is unique, and it’s completely normal to seek solutions that resonate with your personal journey. Whether you’re addressing physical symptoms, emotional balance, or mental clarity, it's important to honor this stage in a way that aligns with your overall well-being.

Addressing the Root Cause, Not Just the Symptoms

Rather than introducing synthetic or plant-based hormones into your body, Femmenessence works by nourishing the Hypothalamus-Pituitary-Thyroid-Adrenal-Ovarian (HPTAO) axis—the system responsible for regulating hormone production. By supporting this critical axis, Femmenessence helps your body naturally increase or decrease certain hormone levels as needed, creating balance from within.

A Personalized Approach to Menopause

Every woman’s body is unique, and so is her experience of menopause. Some women need support for hot flashes and mood swings, while others are focused on heart and bone health, emotional well-being, or sexual health. Femmenessence doesn’t offer a one-size-fits-all solution. Instead, it empowers your body to restore its natural harmony, providing relief where it’s needed most.

Clinically Proven to Work

Femmenessence is backed by published clinical research showing statistically significant relief from menopausal symptoms. Nearly 9 out of 10 women experienced an 80-90% reduction in symptoms like hot flashes and night sweats. In addition, Femmenessence supports broader health benefits, including improved heart health, bone density, energy, and mental well-being. Our unique blend of maca is 10 times more concentrated than raw maca, making it easier for your body to absorb and benefit from.

Why Femmenessence Is Different

Femmenessence doesn’t introduce exogenous hormones into your body. Instead, it works by nourishing the HPTAO axis, allowing your body to adapt naturally. Whether you need more or less of certain hormones, Femmenessence helps your body find balance.

Unlike hormone therapies that flood the body with exogenous hormones, Femmenessence supports your endocrine system’s ability to produce and manage hormones on its own—addressing the root cause of hormone imbalance. This approach not only provides relief from menopausal symptoms but also contributes to overall health, including cholesterol, bone density, energy levels, and more.

To learn more about how to reframe menopause and explore whether hormone therapy is right for you, check out this article on Reframing Menopause.

Dosage and Recommendations

  • Standard Dose: 2 capsules twice daily with 8-12 oz. of water, ideally on an empty stomach. Take the first dose in the morning before breakfast and the second dose early in the afternoon or before your afternoon energy slump. Avoid taking it late in the day to prevent interference with sleep.
  • Light Dose: For those sensitive to herbs or on certain medications, start with 1 capsule in the morning and 1 capsule in the afternoon for two weeks and then increase to the standard dose.
  • Maintenance Dose: After 6-9 months, if you’re experiencing balance, you can reduce your dose by half.

Important Considerations:Femmenessence should not be taken while pregnant or nursing, unless advised by a healthcare professional. Avoid taking it with hormone-suppressing medications like Tamoxifen.

  • To me, health is more than the absence of disease. It’s the vibrant spectrum of physical, emotional, mental, and spiritual aspects that work together like a symphony. Femmenessence allows for this whole-self integration by nourishing the endocrine system. As I go through the journey of perimenopause, I am grateful to be able to bring in the innate wisdom of plants to naturally allow my own inner wisdom to express!

    Dr. Deanna Minich

    Healthcare Provider

    Dr. Deanna Minich

  • I have used Femmenessence for 8 years in my women's health practice. It has become a mainstay botanical approach for my peri- and postmenopausal patients. I also often use Femmenessence for added heart and bone health support. I am a big advocate of Femmenessence, as it has given me a tool I didn't have to help me, help more women.*

    Kathrym Landherr

    Healthcare Provider

    Kathrym Landherr

  • Before I recommend hormones or herbs, I begin the process of supporting a patient’s hormonal balance with Femmenessence. In conjunction with lifestyle modification, this plant-based intervention serves to re-educate the complex feedback loops between her brain and endocrine system. In this way, we are leveraging the power of natural medicine to heal. In 6 years of clinical use of this product, the results, within two cycles, remain astounding.

    Kelly Brogan

    Healthcare Provider

    Kelly Brogan

  • It’s a rare occurrence in medicine when you can find a non-prescription supplement that helps women to the point where it becomes one of your primary go-to’s for hormone health. I have wholeheartedly endorsed Femmenessence® for the past 6 years, not just because of their mission statement and desire to help women, but also because of the research, time, care, foundations and scientific evidence they’ve invested in improving women’s health. I highly encourage every one of my patients, whether they’re pre-menopausal or menopausal or even those with PMS, irregular periods, and other hormonal imbalances, to try Femmenessence.

    Shawn Tassone

    Healthcare Provider

    Shawn Tassone

Quality has been at the heart of all that we do at Symphony Natural Health, since our founding in 1997. We started as a raw material supplier, providing hundreds of tons of herbs from Vanuatu, Australia and France to some of the biggest herbal extraction companies in the world.  Over the next several decades, we’ve grown into a fully vertically integrated company, controlling every step of the process—from seed to shelf. With our own farms, manufacturing, packaging, and fulfillment centers spanning seven countries, we believe that producing the highest-quality products isn’t just about getting one thing right—it’s about getting everything right.

ATTENTION TO DETAIL

Our process begins with researching each plant's unique biology and chemistry, to identify the key biomarkers that deliver real benefits. From there, we carefully select the best   varieties or phenotypes and find the ideal growing conditions—whether that’s soil, climate, or elevation—to ensure the potency of every plant. We also test the soil for heavy metals, pesticides and other potential contaminants to ensure our products are as clean and safe as possible.  When harvest time arrives, we assess the optimal time of the season, time of the day (diurnal cycle), plant growth stage and harvest method to maximize the active ingredients in the plant.

SUSTAINABLE, ORGANIC FARMING PRACTICES

Sustainability isn’t just a buzzword for us—it’s essential to ensure our farms thrive for generations to come. By following the traditional, time-tested practices like crop rotation and soil rejuvenation, we maintain the health of our farms in places like Peru, Vanuatu and France, where crops have been harvested in some cases for thousands of years. We also understand the benefits of organic farming for both higher plant quality and purity; all of our farms are organically certified or in transition to becoming organically certified.

NOVEL, SUPERIOR HARVESTING, DRYING AND MANUFACTURING PROCESSES

Each plant we work with requires a unique harvesting, drying, and manufacturing process to optimize the full spectrum of key active ingredients and bioavailability. These proprietary processes that only use water, temperature, and pressure, result in concentrated levels of active ingredients up to 10 times higher than normal raw materials delivering more potent, bioavailable products without any chemicals or solvents.

100% NATURAL, PURE, VEGAN, KOSHER AND ORGANIC

Every Symphony Natural Health product is certified USDA organic,  Kosher,  and Non-GMO. Our entire line of products are completely vegan and contain no chemicals, solvents, excipients, preservatives, colors, flavors or fillers. You’ll find nothing but pure, organic herbal powder and an organic vegan capsule in every box.  

LOW FODMAP AND FREE OF ALL COMMON ALLERGENS

Symphony products are free from gluten, wheat, yeast, soy, nuts, corn, and dairy, and are third-party verified as low FODMAP—making them safe for those with sensitivities.

PACKAGING FOR MAXIMUM STABILITY AND FRESHNESS

Every detail matters—including how we package our products. Our commitment to wellness, wisdom, and consciousness is reflected in everything we do, from the products we create to the way we deliver them to you.

Just as every transformation begins with a seed, our packaging is as mindful and deliberate as the products themselves. The seed symbolizes infinite potential and growth, and we bring that same care to how we protect your wellness journey.

Our packaging isn’t just functional; it’s an extension of our energy and purpose. With the same mindfulness and intention we put into our products, we use oxygen- and moisture-resistant blister packs, along with UV-shielding boxes, to ensure every capsule remains as fresh and potent as the first. This thoughtful design preserves the quality, effectiveness, and energy of every dose—right up to the very last capsule.

THIRD-PARTY CERTIFICATIONS, TESTING AND QUALITY ASSURANCE

Our manufacturing facilities are GMP and HACCP certified, and every batch is rigorously tested by third-party laboratories to verify its purity, potency, and safety. We also ensure compliance with California’s Proposition 65 for heavy metals. With years of clinical trials, as well as pharmacology and toxicology research, you can trust that Femmenessence is not only effective but held to the highest standards of quality and safety.

What Sets Us Apart – Our Medical Team

Your health journey is unique, and the right support matters. With over 200 years of combined experience, our expert Medical Team has guided more than 150,000 individuals. We're here to provide personalized care, ensuring you feel supported and empowered every step of the way. Gain special access to personalized guidance from our Medical Team when you join our community. We're here to help you find the right dose, manage supplement interactions and provide expert advice to optimize your health journey.

Medical Team

Meet our medical team

  • Dr. Deanna Minich

    Ph.D., Nutrition Scientist

  • Dr. Wendy Warner

    Gynecologist

  • Dr. Tori Hudson

    Naturopathic Doctor

  • Dr. Kim Ross

    Doctor of Clinical Nutrition

  • Dr. Mona Fahoum

    Naturopathic Doctor

  • Dr. Corey Schuler

    Nurse Practitioner & Nutritionist

  • Jan Roberts

    Pharmacist & Clinical Nutritionist

  • Dr. Marc Sklar

    Fertility Expert

  • Dr. Catherine Darley

    Naturopathic Doctor

WHAT MAKES OUR MEDICAL TEAM SO SPECIAL

Available at these grocers and wellness centers

Fruitful Yield Health Foods
New Seasons Market
Mother's Market and Kitchen
Whole Foods Market
Shirlyns Natural Foods
Harmons Grocery

FAQs

How is Femmenessence® MacaLife® different from other perimenopause supplements?

Most perimenopause supplements add hormones (synthetic or plant-based) or rely on generic maca powders that have never been clinically tested in the women they’re intended for.

Femmenessence® is different.

Femmenessence is the first natural product with published double-blind, placebo-controlled human clinical trials showing statistically significant changes in key hormones in both peri- and postmenopausal women.*

MacaLife® uses the same scientific approach: a proprietary, phenotype-specific formulation crafted for the unique hormonal patterns of perimenopause. Instead of adding hormones, Femmenessence supports the body’s own hormone production and communication, addressing the root cause of perimenopausal shifts.*

This combination of life-stage targeting, clinical research and real-world results is what makes Femmenessence stand apart.

How long will it take before I notice results?

In published clinical trials, 74–82% of perimenopausal women reported improvements in symptoms within 2 days to 8 weeks, with many noticing changes around 21 days (one box).*

Because perimenopause is a dynamic transition, every woman’s experience is unique. Some notice shifts quickly, while others may need more time as their endocrine system adapts to changing hormone patterns.

Factors such as stress levels, sleep, hydration, dose timing, and overall health history can all influence how quickly your body responds.

Many women continue to see deeper, more consistent benefits over several cycles, and our Medical Team is always available to help personalize your approach for the best results.*

What symptoms can MacaLife® help support?

In published clinical research on perimenopausal women, Femmenessence® MacaLife® supported improvements in:*

  • Hot flashes & night sweats*
  • Sleep quality and restfulness*
  • Mood fluctuations & emotional steadiness*
  • Energy and daily vitality*
  • Cycle-related changes and irregularities*
  • Occasional anxiousness and stress*
  • Cognitive clarity*

Clinical trials also showed statistically significant support for estradiol, progesterone, and broader endocrine communication, as well as positive shifts in cardiovascular and metabolic wellness markers—all important during perimenopause.*

Is MacaLife® safe to take with other medications?

In most cases, Femmenessence® can be taken alongside supplements or over-the-counter medications. To support optimal absorption, we recommend taking MacaLife® at least one hour apart from other supplements or medications.

Because every woman’s perimenopause experience and health history is unique, it’s always best to consult your healthcare provider before beginning any new supplement.

As a precaution, Femmenessence should not be used with:

  • Tamoxifen
  • Hormone-suppressing medications

Our Medical Team is available if you have questions about how to incorporate MacaLife® into your current routine or need personalized guidance.*

Do I need to take MacaLife® forever?

Not necessarily. Most women take the full serving for 6–9 months, then transition to a maintenance dose as their perimenopause patterns stabilize.

Because perimenopause can last several years and hormone patterns continue to shift, many women choose to maintain ongoing support through this transition.*

You can also adjust your routine over time. Our Medical Team is available to help personalize your approach based on your symptoms, cycle patterns, and health goals.*

What makes MacaLife® clinically proven?

Femmenessence® MacaLife® is one of the few natural products with double-blind, placebo-controlled human clinical trials conducted on the actual formulation you’re taking—specifically in perimenopausal women.

Published research demonstrated statistically significant support for key hormone markers, including estradiol and progesterone, as well as improvements in validated symptom scores (74–82% of women). Studies also showed benefits for cardiovascular markers, metabolic wellness, and overall quality of life during perimenopause.*

This combination of formulation-specific research, life-stage targeting, and published results makes MacaLife® uniquely credible in the perimenopause space.*

How do I take MacaLife®?

Take 1 capsule, twice daily with 8–16 oz. of water, ideally before or between meals.

  • Take the first capsule in the morning
  • Take the second capsule in the afternoon, ideally 30 minutes before your typical low-energy time

Not to be taken in conjunction with hormone-suppressing medications such as Tamoxifen. 

Not to be taken if nursing or past the second trimester of pregnancy, unless advised by your healthcare professional. 

Please consult your healthcare provider before starting Femmenessence if you are taking any medications.

Our Medical Team is always available to help tailor your routine.*

What if MacaLife® doesn’t work for me?

Perimenopause is a constantly shifting transition, and women respond at different speeds. Some notice improvements quickly, while others may need several weeks or cycles as their hormone patterns begin to rebalance.

If you’re not seeing changes right away, our Medical Team can help fine-tune your routine. Adjusting factors such as hydration, dose timing, consistency, and simple lifestyle elements often helps women achieve better results.

With Medical Team support, success rates have reached up to 95%, especially when women receive guidance tailored to their personal hormone patterns.*

You don’t have to navigate perimenopause alone — we’re here to support you.

Will Femmenessence® MacaLife® upset my digestive system?

Most women tolerate MacaLife® well. Occasionally, during the early stages of perimenopause support, some may experience mild digestive changes as their body adjusts.

If this happens, you can try:

  • Reducing your serving size by half until symptoms subside
  • Taking MacaLife® with food for the first 7–10 days, then returning to between-meal timing
  • Adding a probiotic to support digestion
  • Incorporating Sole therapy to support hydration and nutrient absorption

These adjustments often help ease the transition. And if you’d like guidance tailored to your perimenopause symptoms, our Medical Team is available to help.*