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Published Clinical Research Articles


Femmenessence Post Menopause

Maca-GO® as referenced in all the below medical journal publications, is a Symphony Natural Health proprietary ingredient and only available in our products. Maca-GO® is the sole ingredient in Femmenessence MacaPause® and is a proprietary combination of the different phenotypes of the herb maca (Lepidium peruvianum) specifically for hormone balance in women. Maca-GO® is sourced from our organic farms in Peru and then goes through our proprietary, 100% natural, manufacturing processes that is GMP, Organic and Kosher certified. This process concentrates the full spectrum of active ingredients and maximizes the bioavailability.

Maca-GO® is the ONLY clinically proven natural product that has demonstrated statistically significant effects on hormones in peri and post menopausal women. Our clinical trials also demonstrated that Maca-GO® has the highest success rate (84%) of any herbal product in the world in reducing menopausal symptoms in postmenopausal women as well as benefits for heart, bone and mental health.

Articles

Maca-GO White Paper – Clinical Effects of a Proprietary, Standardized, Concentrated, Organic Lepidium peruvianum Formulation (Maca-GO) as an Alternative to HRT by Ronald Carter, M.D.

Toru Tabei, M.D.Ph.D. Recent Topics in Western Countries: Effect of Maca-GO upon Menopausal Symptoms

Journal of The Japan Menopause Society April 2010. Vol. 18, No. 1, pp. 49-56

Meissner H.O., Mrozikiewicz P., Bobkiewicz-Kozlowska T., et al. Hormone-balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon: (Part I.) Biochemical and Pharmacodynamic Study on Maca using Clinical Laboratory Model on Ovariectomized Rats.
International Journal of Biomedical Science 2006: Vol. 2, No. 3. 260-72

Meissner H.O., Mscisz A., Reich-Bilinska H., et al. Hormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon): (II) Physiological & symptomatic responses of early-postmenopausal women to standardized doses of Maca in Double Blind, Randomized, Placebo-Controlled, Multi-Centre Clinical Study.
International Journal of Biomedical Science, Dec. 2006: Vol. 2 No. 4, 360–74.

Meissner H.O., Mscisz A., Reich-Bilinska H., et al. Hormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon): (III) Clinical responses of early-postmenopausal women to Maca in double blind, randomized, Placebo-controlled, crossover configuration, outpatient study.
International Journal of Biomedical Science., Dec. 2006: Vol. 2 No. 4, 375–94.

Meissner, Henry. (2019). Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii) Meissner HXu LWan WYi F Phytochemistry Letters 2019 vol: 31 pp: 208-216. Phytochemistry Letters. 31. 208-216. 10.1016/j.phytol.2019.04.011.

Meissner H.O., Reich-Bilinska H., Mrozikiewicz P., et al. Hormone-balancing and Pharmacological Effects of Therapeutic Doses of Lepidium peruvianum (Maca-GO) in Postmenopausal Women.
Menopause. 2005; Vol. 12, No. 6. p. 813.

Meissner H.O., Kapczynski W., Mscisz A., Lutomski J. Use of Gelatinized Maca (Lepidium peruvianum) in Early Postmenopausal Women – a Pilot Study.
International Journal of Biomedical Science. 2005; Vol. 1, No. 1. p. 33-45.

Meissner H.O., Reich-Bilinska H., Kedzia B., Mscisz A. Pre-Gelatinised Maca (Lepidium peruvianum Chacon) As Non-Hormonal Herbal Remedy to Treat Menopausal Symptoms in
Pre- and Post-Menopausal Women.

Meissner H.O., Mscisz A., Kedzia B., et al. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically Synonymous? International Journal of Biomedical Science, Mar. 2015: Vol. 11, No. 1. 1-15

Meissner H.O., Kedzia B., Mrozikiewicz P.M., Mscisz A. Short and Long-Term Physiological Responses of Male and Female Rats to Two Dietary levels of Pre-Gelatinized Maca (Lepidium peruvianum Chacon).
International Journal of Biomedical Science. 2006; 1 (2): 61-78.2006 Vol. 2, No. 1. 13–28.

Meissner H.O., Mscisz A., Mrozikiewicz P.M., et al. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes.
International Journal of Biomedical Science, Sept. 2015. Vol. 11, No. 3. 131-45

Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations.
Int J Biomed Sci Vol. 12 No. 1 March 2016. (Meissner HO, Mscisz A, Piatkowska E, et al.)

Peruvian Maca (Lepidium peruvianum) - III: The Effects of Cultivation Altitude on Phytochemical and Genetic Differences in the Four Prime Maca Phenotypes.
Int J Biomed Sci Vol. 13 No. 2 June 2017. (Meissner HO, Mscisz A, Baraniak M, et al.)


Femmenessence Perimenopause

Maca-GO® as referenced in all the below medical journal publications, is a Symphony Natural Health proprietary ingredient and only available in our products. Femmenessence MacaLife®, our product for perimenopausal women, is made up of 25% Maca-GO® and 75% one other maca phenotype that we have seen in research is ideal to reduce menopausal symptoms.

 

Maca-GO® is the ONLY clinically proven natural product that has demonstrated statistically significant effects on hormones in peri and post menopausal women. Our clinical trials also demonstrated that Maca-GO® has the highest success rates (74-82%) in reducing menopausal symptoms in perimenopausal women as well as benefits for heart and mental health.

Article

Maca-GO White Paper – Clinical Effects of a Proprietary, Standardized, Concentrated, Organic Lepidium peruvianum Formulation (Maca-GO) as an Alternative to HRT by Ronald Carter, M.D.

Meissner H.O., Reich-Bilinska H., Mscisz A., Kedzia B. Therapeutic effect of Lepidium peruvianum Chacon (Pre-Gelatinised Maca) used as a non-hormonal alternative to HRT in
Peri-menopausal women - Clinical Pilot Study.
International Journal of Biomedical Science 2006: Vol. 2, No. 2. 143-59.

Meissner, Henry. (2019). Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii) Meissner HXu LWan WYi F Phytochemistry Letters 2019 vol: 31 pp: 208-216. Phytochemistry Letters. 31. 208-216. 10.1016/j.phytol.2019.04.011.

Meissner H.O., Reich-Bilinska H., Kedzia B., Mscisz A. Pre-Gelatinised Maca (Lepidium peruvianum Chacon) As Non-Hormonal Herbal Remedy to Treat Menopausal Symptoms in
Pre- and Post-Menopausal Women.
Basic & Clinical Pharmacology & Toxicology. 2005; Vol. 97, Supp l (1): 48.

Meissner H.O., Kapczynski W., Mscisz A., Lutomski J. Use of Gelatinized Maca (Lepidium peruvianum) in Early Postmenopausal Women – a Pilot Study. International Journal of Biomedical Science. 2005; 1 (1): 33-45.

Meissner H.O., Kedzia B., Mrozikiewicz P.M., Mscisz A. Short and Long-Term Physiological Responses of Male and Female Rats to Two Dietary levels of Pre-Gelatinized Maca (Lepidium peruvianum Chacon).
International Journal of Biomedical Science. 2006; 1 (2): 61-78.2006 Vol. 2, No. 1. 13–28.

Meissner H.O., Mscisz A., Mrozikiewicz P.M., et al. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes.
International Journal of Biomedical Science, Sept. 2015. Vol. 11, No. 3. 131-45

Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations.
Int J Biomed Sci Vol. 12 No. 1 March 2016. (Meissner HO, Mscisz A, Piatkowska E, et al.)

Peruvian Maca (Lepidium peruvianum) - III: The Effects of Cultivation Altitude on Phytochemical and Genetic Differences in the Four Prime Maca Phenotypes.
Int J Biomed Sci Vol. 13 No. 2 June 2017. (Meissner HO, Mscisz A, Baraniak M, et al.)

Toru Tabei, M.D.Ph.D. Recent Topics in Western Countries: Effect of Maca-GO upon Menopausal Symptoms
Journal of The Japan Menopause Society April 2010. Vol. 18, No. 1, pp. 49-56

Meissner H.O., Mscisz A., Kedzia B., et al. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically Synonymous?
International Journal of Biomedical Science, Mar. 2015: Vol. 11, No. 1. 1-15.


Femmenessence Menstrual and Reproductive Health

Femmenessence Harmony contains the proprietary ingredient MacaHarmony which is only available in our products. Maca-GO was originally the sole ingredient in Femmenessence MacaHarmony however due to additional research into different maca phenotypes the formulation in Femmenessence MacaHarmony was modified to include 75% Maca-GO and 25% of a proprietary maca phenotype combination focused on focused on fertility, PMS and bone health.

Below is a White Paper summary discussing all of the research in easy to follow terms and goes through the history of our research. This is the ideal first paper to read from the below list:

Article

Maca-GO White Paper – Clinical Effects of a Proprietary, Standardized, Concentrated, Organic Lepidium peruvianum Formulation (Maca-GO) as an Alternative to HRT by Ronald Carter, M.D.

Meissner, Henry. (2019). Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii) Meissner HXu LWan WYi F Phytochemistry Letters 2019 vol: 31 pp: 208-216. Phytochemistry Letters. 31. 208-216. 10.1016/j.phytol.2019.04.011.

Meissner H.O., Reich-Bilinska H., Kedzia B., Mscisz A. Pre-Gelatinised Maca (Lepidium peruvianum Chacon) As Non-Hormonal Herbal Remedy to Treat Menopausal Symptoms in
Pre- and Post-Menopausal Women.

Meissner H.O., Kedzia B., Mrozikiewicz P.M., Mscisz A. Short and Long-Term Physiological Responses of Male and Female Rats to Two Dietary levels of Pre-Gelatinized Maca (Lepidium peruvianum Chacon).
International Journal of Biomedical Science. 2006; 1 (2): 61-78.2006 Vol. 2, No. 1. 13–28.

Meissner H.O., Mscisz A., Mrozikiewicz P.M., et al. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes.
International Journal of Biomedical Science, Sept. 2015. Vol. 11, No. 3. 131-45

Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations.
Int J Biomed Sci Vol. 12 No. 1 March 2016. (Meissner HO, Mscisz A, Piatkowska E, et al.)

Peruvian Maca (Lepidium peruvianum) - III: The Effects of Cultivation Altitude on Phytochemical and Genetic Differences in the Four Prime Maca Phenotypes.
Int J Biomed Sci Vol. 13 No. 2 June 2017. (Meissner HO, Mscisz A, Baraniak M, et al.)

Meissner H.O., Mscisz A., Kedzia B., et al. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically Synonymous?
International Journal of Biomedical Science, Mar. 2015: Vol. 11, No. 1. 1-15.

Ruiz-luna AC, Salazar S, Aspajo NJ, Rubio J, Gasco M, Gonzales GF. Lepidium meyenii (Yellow Maca) increases litter size in normal adult female mice. Reproductive Biology and Endocrinology 2005; 3:16.

Uchiyama F, Jikyo T, Takeda R, Ogata M. Lepidium meyenii (Maca) enhances the serum levels of luteinising hormone (LH) in female rats. Journal of Ethnopharmacology. 2014;151(2):897-902.


Revolution MacaLibrium

Please note: The following research articles used various forms and phenotypes of maca. Therefore, consumers may experience different results when using Revolution Macalibrium, which was formulated using specific phenotypes selected for men's health and improved bioavailability.

Article

Gonzales GF, Cordova A, Vega K, et al. Effect of Lepidium meyenii (Maca) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men.
Andrologia. 2002; 34:367-72.

Gonzales GF, Cordova A, Vega K, et al. Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enhancing properties, on serum reproductive hormone levels in adult
healthy men.
J Endocrinol. 2003; 176: 163–8.

Gonzales GF, Vanessa Vasquez, Daniella Rodriguez, Carmen Maldonado, Juliet Mormontoy, Jimmy Portella, Monica Pajuelo, León Villegas, Manuel Gasco, P.P. Mathur Effect of two different extracts of red maca in male rats with testosterone-induced prostatic hyperplasia. 2007; Vol. 9, No. 2 p. 245-51

G F Gonzales, M Gasco, A Córdova, A Chung, J Rubio and L Villegas Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats 1: Asian J Androl. 2001 Sep; 3(3):231-3

Gonzales GF, Cordova A, Gonzales C, et al. Lepidium meyenii (Maca) improved semen parameters in adult men. Asian J Androl. 2002; 3:301–3.

Gonzales GF, Gasco M, Cordova A, et al. Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats acutely exposed to high altitude (4340 m). J Endocrinol. 2004; 180:87–95.

Basic & Clinical Pharmacology & Toxicology. 2005; Vol. 97, Supp l (1): 48.

Meissner H.O., Kedzia B., Mrozikiewicz P.M., Mscisz A. Short and Long-Term Physiological Responses of Male and Female Rats to Two Dietary levels of Pre-Gelatinized Maca (Lepidium peruvianum Chacon).
International Journal of Biomedical Science. 2006; 1 (2): 61-78.2006 Vol. 2, No. 1. 13–28.

Meissner, Henry. (2019). Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii) Meissner HXu LWan WYi F Phytochemistry Letters 2019 vol: 31 pp: 208-216. Phytochemistry Letters. 31. 208-216. 10.1016/j.phytol.2019.04.011.

Meissner H.O., Mscisz A., Mrozikiewicz P.M., et al. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes.
International Journal of Biomedical Science, Sept. 2015. Vol. 11, No. 3. 131-45

Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations.
Int J Biomed Sci Vol. 12 No. 1 March 2016. (Meissner HO, Mscisz A, Piatkowska E, et al.)

Peruvian Maca (Lepidium peruvianum) - III: The Effects of Cultivation Altitude on Phytochemical and Genetic Differences in the Four Prime Maca Phenotypes.
Int J Biomed Sci Vol. 13 No. 2 June 2017. (Meissner HO, Mscisz A, Baraniak M, et al.)

Meissner H.O., Mscisz A., Kedzia B., et al. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically Synonymous?
International Journal of Biomedical Science, Mar. 2015: Vol. 11, No. 1. 1-15.


Herbatonin

Herbatonin® or plant melatonin has been found in several plants (Dubbels et al., 1995; Hattori et al, 1995). The hormone is also present in algae, where its role may be acting as a phytohormone and anti-oxidant (Balzer and Hardeland, 1996). Amount varies in different species, from 0 to 800 pg/mg protein, with the highest amount found in rice family Gramineae.

The identity of plant melatonin was verified by HPLC. Biological and pharmacological identity with animal melatonin was demonstrated by activity in chicks and rabbits. Dietary (ingested) plant melatonin influences plasma levels and brain receptor binding. Some selected references related to the existence of plant melatonin and the action of Melatonin in in-vivo laboratory models and in humans are included below:

Article

et al. Abnormal melatonin synthesis in autism spectrum disorders. Mol Psychiatry. 2008 Jan;13(1):90-8. Epub 2007 May 15.

Arendt, J. (1994) Human responses to light and melatonin, pp 439-442 in: “Advances in Pineal Research”, Vol 8, Eds: M. Moller and P. Pevet, J. Libbey, London.

Arendt, J. (1995) Significance of melatonin in humans, pp 165-171 in: “The Pineal Gland and its Hormones” Eds: Fraschini, F., Reiter, R.J. and Stankov, B., Plenum Press, New York.

Armstrong, S. M. (1991) Treatment of sleep disorders by melatonin administration, pp 263-274 in: “Advances in Pineal Research,” Vol.6, Eds: A. Foldes and R. J. Reiter, John Libbey, London.

Balzer, I. and Hardeland, R. (1996) Melatonin in algae and higher plants - possible roles as a phytohormone and antioxidant. Botanica Acta 109: 180-183.

Blask, D.E. and Wilson, S.T. (1995) Melatonin action on human breast cancer cells: involvement of glutathione metabolism and the redox environment. pp 209-217 in: “The Pineal Gland
and its Hormones” Eds: Fraschini, F., Reiter, R.J. and Stankov, B., Plenum Press, New York.

Cagnoni, M.L., Lombardi, A., Cerinic, et al. (1995) Melatonin for treatment of chronic refractory sarcoidosis, Lancet, 346 (8984): 1229-1230.

Chan, T.Y. and Tang, P.L. (1995) Effect of melatonin on the maintenance of cholesterol homeostasis in the rat, Endocrine Res. 21: 681-696.

Chaste P.et al. Genetic variations of the melatonin pathway in patients with attention-deficit and hyperactivity disorders. J Pineal Res. 2011 Apr 27. [Epub]

Dubbels, R., Reiter, R.J., Klenke, E., Goebel, A., Schnakenberg, E., Ehlers, C., Schiwara, H.W. and Schloot, W. (1995) Melatonin in edible plants identified by radioimmunoassay and by
high performance liquid chromatography-mass spectrometry, J. Pineal Res. 18: 28-31.

Escames G, et al. The role of mitochondria in brain aging and the effects of melatonin.CurrNeuropharmacol. 2010 Sep;8(3):182-93.

Folkard, S., Arendt, J. and Clark, M. (1993) Can melatonin improve shiftworkers tolerance of the night shift? Some preliminary findings, Quoted in Arendt, J (1994) Human responses to
light and melatonin Advances in Pineal Research, Vol 8, Eds: M. Moller and P. Pevet, J. Libbey, London.

Frye RE. Melatonin in autism spectrum disorders: a systematic review and meta-analysis. Dev Med Child Neurol. 2011 Apr 19. doi: 10.1111/j.1469-8749.2011.03980.x. [Epub]

Guardiola-Lemaitre, B. (1994) Melatonin agonist/antagonist: from the receptor to therapeutic applications, in: “Advances in Pineal Research”, Vol 8, Eds: M. Moller and P. Pevet,
pp 333-348, J. Libbey, London.

Hattori, A., Migitaka, H., Iigo, M., Itoh, M., Yamamoto, K., Ohtani-Kaneko, R., Hara, M., Suzuki, T. and Reiter, R.J. (1995) Identification of melatonin in plants and its effects on plasma
melatonin levels and binding to melatonin receptors in vertebrates, Biochem. Mol. Biol. Int. 35: 627-634.

Huber CG. The role of melatonin in glaucoma: implications concerning pathophysiological relevance and therapeutic potential. J Pineal Res. 2011 Jan;50(1):1-7.

Iguchi, H. et al. Age-Dependent Reduction in Serum Melatonin Concentrations in Healthy Human Subjects. The Journal of Clinical Endocrinology & Metabolism. July 1, 1982 vol. 55 no. 1 27-29.

Jean‐Louis, G. , Gizycki, H. and Zizi, F. (1998), Melatonin effects on sleep, mood, and cognition in elderly with mild cognitive impairment. Journal of Pineal Research, 25: 177-183. doi:10.1111/j.1600-079X.1998.tb00557.x

Kaczor, T. An Overview of Melatonin and Breast Cancer. Natural Medicine Journal 2010 Feb.[Epub]

Knutsson, A. Health disorders of shift worker. Occupational Medicine 2003;53:103–10

Kumar A, SharmaSS.Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF-κB and Nrf2 cascades. J Pineal Res. 2011 Mar;50(2):124-31.

Lewy AJ, Low, but not high, doses of melatonin entrained a free-running blind person with a long circadian period. Chronobiol Int. 2002 May;19(3):649-58.

Lissoni, P., Barni, S., Fossati, V.,Ardizzoia, A., et al. (1995) A randomized study of neuroimmunotherapy with low dose subcutaneous interleukin-2 plus melatonin compared to
supportive care alone in patients with untreatable metastatic solid tumour, Support Care Cancer, 3: 194-197.

Maestroni, G.J.M., Conti, A. et al (1994) pp 73-81 in: “Advances in Pineal Research” vol 7, Eds: Maestroni, G.J.M., Conti, A & Reiter, R.J. John Libbey, London.

Melatonin treatment improves blood pressure, lipid profile, and parameters of oxidative stress in patients with metabolic syndrome. J Pineal Res. 2011 Apr;50(3):261-6. Epub 2010 Dec 8.

Nagtegaal.E., Smits, M., Swart,W., van der Meer, G., and Kerkhof, G.(1995) Melatonin secretion and coronary heart disease, Lancet 346 (8985): 1299.

Oaknin-Bendahan, S, Anis, Y, Nir, et al.(1995) Effects of long-term administration of melatonin and a putative antagonist on the ageing rat, Neuroreport, 6: 785-8.

Ochoa, J. J., Díaz‐Castro, J. , Kajarabille, N. , García, C. , Guisado, I. M., De Teresa, C. and Guisado, R. (2011), Melatonin supplementation ameliorates oxidative stress and inflammatory signaling induced by strenuous exercise in adult human males. Journal of Pineal Research, 51: 373-380. doi:10.1111/j.1600-079X.2011.00899.x

Parkes, J.D. (1995) Melatonin and sleep, pp 183-198 in: “The Pineal Gland and its Hormones” Eds: Fraschini, F., Reiter, R.J. and Stankov, B., Plenum Press, NY.

Pierpaoli, W., Dall’Ara, A., Pedrinis, E., and Regelson, W. (1991) The pineal control of ageing. The effects of melatonin and pineal grafting on the survival of older mice, Ann. N.Y. Acad.
Sci, 621: 291-313.

et al. Possible therapeutic value of melatonin in mild cognitive impairment: a retrospective study. J Pineal Res. 2007 Nov;43(4):404-9.

Potential of melatonin to treat or prevent age-related macular degeneration through stimulation of telomerase activity.Med Hypotheses. 2011 Jan;76(1):79-85

et al. Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period. J Matern Fetal Neonatal Med. 2011 May 11. [Epub]

Powell, D. W., (2004) pp 39-42 Endocrinology & Naturopathic Therapies 6th Edition

et al. Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease. J Pineal Res. 2009 Aug;47(1):82-96. Epub 2009 Jun 17.

et al. Melatonin effects on sleep, mood, and cognition in elderly with mild cognitive impairment. J Pineal Res. 1998 Oct;25(3):177-83

et al. Melatonin in mitochondrial dysfunction and related disorders.Int J Alzheimers Dis. 2011;2011:326320. Epub 2011 May 4.

Robinson, W.A., Dreiling, L., Gonzalez, R. and Balmer, C. (1995) Treatment of human metastatic malignant melanoma with highdose oral melatonin, pp 219-225 in: “The Pineal Gland
and its Hormones” Eds: Fraschini, F., Reiter, R.J. and Stankov, B., Plenum Press, New York.

The Sleep Disorders Inventory: an instrument for studies of sleep disturbance in persons with Alzheimer's disease.J Sleep Res. 2003 Dec;12(4):331-7.

Vijayalaxmi, Reiter, et al (1995) Marked reduction of radiation-induced micronuclei in human blood lymphocytes pretreated with melatonin, Radiation Res. 143: 102 - 106.

Wetterberg, L. (1995) Seasonal affective disorder, melatonin and light, pp 199-208 in: “The Pineal Gland and its Hormones” Eds: Fraschini, F., Reiter, R.J. and Stankov, B., Plenum Press, New York

Zhdanova IV, et al. Effects of a low dose of melatonin on sleep in children with Angelman syndrome. J PediatrEndocrinolMetab. 1999 Jan-Feb;12(1):57-67.

Zhdanova IV, et al. Melatonin Treatment for Age-Related Insomnia. J ClinEndocrinolMetab, October 2001, 86(10):4727–4730


pH Quintessence

Below are a list of publications which relate to pH Quintessence:

Article

P. R. Cheeke (1983). Biological Properties and Nutritional Significance of Legume Saponins. Chapter 21, in Leaf Proteins (L. Telek, ed.), A.V.I. Publ. Co., Westport, p.396-414.

H. O. Meissner, R. Carlson and C. Tragardh, (1980). Isolation and purification of proteins from green vegetation for direct human consumption. In: "Food Process Engineering". (P. Linko, Y. Maiki, J. Olkku, Editors) pp. 864-870. Applied Science Publishers Ltd, London.

H. O. Meissner (1989). Commercial Applications of Leaf Protein Research - three faces of industrial leaf fractionation: resources - operation and marketing.. LEAFPRO-89, Pisa, Perugia, Vitterbo-Italy. Italian Journal of Food Science. 1989; p. 360-365.

N.W. Pirie (1987). Leaf Protein and its by-products in human and animal nutrition. London, Cambridge University Press.

H. O. Meissner (1983). Protein Concentrates from Herbage and their Fractionation into Feed- and Food-grade Products. Chapter 15, in: Leaf Proteins (L. Telek, ed.), A.V.I. Publ. Co., Westport, p.437-466.

TGA, Department of Health and Aging, Australian Government. Pure Alfalfa Extract Tablets Medicago sativa (750mg): ARTG registration/listing No: 83132. Supporting evidence for listing of a Therapeutic Preparation. (Canberra, 21 June 2002).