Published Clinical Research Articles

Minich DM, Ross K, Frame J, Fahoum M, Warner W, Meissner HO. Not All Maca Is Created Equal: A Review of Colors, Nutrition, Phytochemicals, and Clinical Uses. Nutrients. 2024;16(4):530. Published 2024 Feb 14.

Ross, K. & Minich, D. Maca-GO®: The Science, Publications, and Clinical Applications for Hormone Health. 2nd ed. May 2023.

Toru Tabei, M.D.Ph.D. Recent Topics in Western Countries: Effect of Maca-GO upon Menopausal Symptoms

Journal of The Japan Menopause Society April 2010. Vol. 18, No. 1, pp. 49-56

Meissner H.O., Mrozikiewicz P., Bobkiewicz-Kozlowska T., et al. Hormone-balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon: (Part I.) Biochemical and Pharmacodynamic Study on Maca using Clinical Laboratory Model on Ovariectomized Rats.
International Journal of Biomedical Science 2006: Vol. 2, No. 3. 260-72

Meissner H.O., Mscisz A., Reich-Bilinska H., et al. Hormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon): (II) Physiological & symptomatic responses of early-postmenopausal women to standardized doses of Maca in Double Blind, Randomized, Placebo-Controlled, Multi-Centre Clinical Study.
International Journal of Biomedical Science, Dec. 2006: Vol. 2 No. 4, 360–74.

Meissner H.O., Mscisz A., Reich-Bilinska H., et al. Hormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon): (III) Clinical responses of early-postmenopausal women to Maca in double blind, randomized, Placebo-controlled, crossover configuration, outpatient study.
International Journal of Biomedical Science., Dec. 2006: Vol. 2 No. 4, 375–94.

Meissner, Henry. (2019). Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii) Meissner HXu LWan WYi F Phytochemistry Letters 2019 vol: 31 pp: 208-216. Phytochemistry Letters. 31. 208-216. 10.1016/j.phytol.2019.04.011.

Meissner H.O., Reich-Bilinska H., Mrozikiewicz P., et al. Hormone-balancing and Pharmacological Effects of Therapeutic Doses of Lepidium peruvianum (Maca-GO) in Postmenopausal Women.
Menopause. 2005; Vol. 12, No. 6. p. 813.

Meissner H.O., Kapczynski W., Mscisz A., Lutomski J. Use of Gelatinized Maca (Lepidium peruvianum) in Early Postmenopausal Women – a Pilot Study.
International Journal of Biomedical Science. 2005; Vol. 1, No. 1. p. 33-45.

Meissner H.O., Reich-Bilinska H., Kedzia B., Mscisz A. Pre-Gelatinised Maca (Lepidium peruvianum Chacon) As Non-Hormonal Herbal Remedy to Treat Menopausal Symptoms in
Pre- and Post-Menopausal Women.

Meissner H.O., Mscisz A., Kedzia B., et al. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically Synonymous? International Journal of Biomedical Science, Mar. 2015: Vol. 11, No. 1. 1-15

Meissner H.O., Kedzia B., Mrozikiewicz P.M., Mscisz A. Short and Long-Term Physiological Responses of Male and Female Rats to Two Dietary levels of Pre-Gelatinized Maca (Lepidium peruvianum Chacon).
International Journal of Biomedical Science. 2006; 1 (2): 61-78.2006 Vol. 2, No. 1. 13–28.

Meissner H.O., Mscisz A., Mrozikiewicz P.M., et al. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes.
International Journal of Biomedical Science, Sept. 2015. Vol. 11, No. 3. 131-45

Meissner H.O., Mscisz A., Piatkowska E., Baraniak M., Mielcarek S., Kedzia B., Holderna-Kedzia E., & Pisulewski P. (2016). Peruvian M,aca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations. International journal of biomedical science : IJBS, 12(1), 9–24.

Meissner H.O., Mscisz A., Baraniak M., Piatkowska E., Pisulewski P., Mrozikiewicz M., & Bobkiewicz-Kozlowska T. (2017). Peruvian Maca (Lepidium peruvianum) - III: The Effects of Cultivation Altitude on Phytochemical and Genetic Differences in the Four Prime Maca Phenotypes. International journal of biomedical science : IJBS, 13(2), 58–73.

Harnly J., Geng P., Sun J., Chen P., Gafner S., Stewart J., Frame J., Meissner H.O. (2018).

Chemical and genetic characterization of Maca (Lepidium meyenii synonym Lepidium peruvianum)

Meissner H.O., Lijia Xu, Wenting Wan, Fan Yi. (2019).

Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii)

Characterization of Maca (Lepidium meyenii/Lepidium peruvianum) Using a Mass Spectral Fingerprinting, Metabolomic Analysis, and Genetic Sequencing Approach

Planta Med. 2020 Jul;86(10):674-685. doi: 10.1055/a-1161-0372. Epub 2020 May 20.

Ping Geng, Jianghao Sun, Pei Chen, Eric Brand, James Frame, Henry Meissner, Jeremy Stewart, Stefan Gafner, Stephanie Clark, Jesse Miller, James Harnly

Tarabasz D, Szczeblewski P, Laskowski T, Płaziński W, Baranowska-Wójcik E, Szwajgier D, Kukula-Koch W, Meissner HO. The Distribution of Glucosinolates in Different Phenotypes of Lepidium peruvianum and Their Role as Acetyl- and Butyrylcholinesterase Inhibitors-In Silico and In Vitro Studies. Int J Mol Sci. 2022 Apr 27;23(9):4858. doi: 10.3390/ijms23094858. PMID: 35563248; PMCID: PMC9101689.

Ross K. Nutritional management of surgically induced menopause: A case report. Womens Health (Lond). 2021 Jan-Dec;17:17455065211031492. doi: 10.1177/17455065211031492. PMID: 34253105; PMCID: PMC8280844.

Minich DM, Ross K, Frame J, Fahoum M, Warner W, Meissner HO. Not All Maca Is Created Equal: A Review of Colors, Nutrition, Phytochemicals, and Clinical Uses. Nutrients. 2024;16(4):530. Published 2024 Feb 14.

Ross, K. & Minich, D. Maca-GO®: The Science, Publications, and Clinical Applications for Hormone Health. 2nd ed. May 2023.

Meissner H.O., Reich-Bilinska H., Mscisz A., Kedzia B. Therapeutic effect of Lepidium peruvianum Chacon (Pre-Gelatinised Maca) used as a non-hormonal alternative to HRT in
Peri-menopausal women - Clinical Pilot Study.
International Journal of Biomedical Science 2006: Vol. 2, No. 2. 143-59.

Meissner, Henry. (2019). Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii) Meissner HXu LWan WYi F Phytochemistry Letters 2019 vol: 31 pp: 208-216. Phytochemistry Letters. 31. 208-216. 10.1016/j.phytol.2019.04.011.

Meissner H.O., Reich-Bilinska H., Kedzia B., Mscisz A. Pre-Gelatinised Maca (Lepidium peruvianum Chacon) As Non-Hormonal Herbal Remedy to Treat Menopausal Symptoms in
Pre- and Post-Menopausal Women.
Basic & Clinical Pharmacology & Toxicology. 2005; Vol. 97, Supp l (1): 48.

Meissner H.O., Kapczynski W., Mscisz A., Lutomski J. Use of Gelatinized Maca (Lepidium peruvianum) in Early Postmenopausal Women – a Pilot Study. International Journal of Biomedical Science. 2005; 1 (1): 33-45.

Meissner H.O., Kedzia B., Mrozikiewicz P.M., Mscisz A. Short and Long-Term Physiological Responses of Male and Female Rats to Two Dietary levels of Pre-Gelatinized Maca (Lepidium peruvianum Chacon).
International Journal of Biomedical Science. 2006; 1 (2): 61-78.2006 Vol. 2, No. 1. 13–28.

Meissner H.O., Mscisz A., Mrozikiewicz P.M., et al. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes.
International Journal of Biomedical Science, Sept. 2015. Vol. 11, No. 3. 131-45

Meissner, H.O., Mscisz, A., Piatkowska, E., Baraniak, M., Mielcarek, S., Kedzia, B., Holderna-Kedzia, E., & Pisulewski, P. (2016). Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations. International journal of biomedical science : IJBS, 12(1), 9–24.

Meissner, H. O., Mscisz, A., Baraniak, M., Piatkowska, E., Pisulewski, P., Mrozikiewicz, M., & Bobkiewicz-Kozlowska, T. (2017). Peruvian Maca (Lepidium peruvianum) - III: The Effects of Cultivation Altitude on Phytochemical and Genetic Differences in the Four Prime Maca Phenotypes. International journal of biomedical science : IJBS, 13(2), 58–73.

Toru Tabei, M.D.Ph.D. Recent Topics in Western Countries: Effect of Maca-GO upon Menopausal Symptoms
Journal of The Japan Menopause Society April 2010. Vol. 18, No. 1, pp. 49-56

Meissner H.O., Mscisz A., Kedzia B., et al. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically Synonymous?
International Journal of Biomedical Science, Mar. 2015: Vol. 11, No. 1. 1-15.

Harnly J., Geng P., Sun J., Chen P., Gafner S., Stewart J., Frame J., Meissner H.O. (2018).

Chemical and genetic characterization of Maca (Lepidium meyenii synonym Lepidium peruvianum)

Meissner H.O., Lijia Xu, Wenting Wan, Fan Yi. (2019).

Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii)

Characterization of Maca (Lepidium meyenii/Lepidium peruvianum) Using a Mass Spectral Fingerprinting, Metabolomic Analysis, and Genetic Sequencing Approach

Planta Med. 2020 Jul;86(10):674-685. doi: 10.1055/a-1161-0372. Epub 2020 May 20.

Ping Geng, Jianghao Sun, Pei Chen, Eric Brand, James Frame, Henry Meissner, Jeremy Stewart, Stefan Gafner, Stephanie Clark, Jesse Miller, James Harnly

Tarabasz D, Szczeblewski P, Laskowski T, Płaziński W, Baranowska-Wójcik E, Szwajgier D, Kukula-Koch W, Meissner HO. The Distribution of Glucosinolates in Different Phenotypes of Lepidium peruvianum and Their Role as Acetyl- and Butyrylcholinesterase Inhibitors-In Silico and In Vitro Studies. Int J Mol Sci. 2022 Apr 27;23(9):4858. doi: 10.3390/ijms23094858. PMID: 35563248; PMCID: PMC9101689.

Minich DM, Ross K, Frame J, Fahoum M, Warner W, Meissner HO. Not All Maca Is Created Equal: A Review of Colors, Nutrition, Phytochemicals, and Clinical Uses. Nutrients. 2024;16(4):530. Published 2024 Feb 14. doi:10.3390/nu16040530

Hayes SK, Manongi S, Ross K. Concentrated Gelatinized Proprietary Phenotype Formulation of Lepidium peruvianum (maca) Positively Impacts Polycystic Ovarian Syndrome (PCOS), Premenstrual Syndrome (PMS), Dysmenorrhea, and Hormone Levels for Fertility Optimization: A Case Report. Gynecol Obstet Open Acc. 2024;8: 177. https://doi.org/10.29011/25772236.100177

Fahoum M, Ross K (2023) An Integrative Approach for Improving and Managing Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD): A Case Report. Curr Res Cmpl Alt Med 7: 211.

Ross K (2023) Improvements in Premenstrual Syndrome, Primary Dysmenorrhea, and Menorrhagia with Natural Therapies: A Case Report. Curr Res Cmpl Alt Med 7: 207

Ross, K. & Minich, D. Maca-GO®: The Science, Publications, and Clinical Applications for Hormone Health. 2nd ed. May 2023.

Meissner, Henry. (2019). Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii) Meissner HXu LWan WYi F Phytochemistry Letters 2019 vol: 31 pp: 208-216. Phytochemistry Letters. 31. 208-216. 10.1016/j.phytol.2019.04.011.

Meissner H.O., Reich-Bilinska H., Kedzia B., Mscisz A. Pre-Gelatinised Maca (Lepidium peruvianum Chacon) As Non-Hormonal Herbal Remedy to Treat Menopausal Symptoms in
Pre- and Post-Menopausal Women.

Meissner H.O., Kedzia B., Mrozikiewicz P.M., Mscisz A. Short and Long-Term Physiological Responses of Male and Female Rats to Two Dietary levels of Pre-Gelatinized Maca (Lepidium peruvianum Chacon).
International Journal of Biomedical Science. 2006; 1 (2): 61-78.2006 Vol. 2, No. 1. 13–28.

Meissner H.O., Mscisz A., Mrozikiewicz P.M., et al. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes.
International Journal of Biomedical Science, Sept. 2015. Vol. 11, No. 3. 131-45

Meissner, H.O., Mscisz, A., Piatkowska, E., Baraniak, M., Mielcarek, S., Kedzia, B., Holderna-Kedzia, E., & Pisulewski, P. (2016). Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations. International journal of biomedical science : IJBS, 12(1), 9–24.

Meissner, H. O., Mscisz, A., Baraniak, M., Piatkowska, E., Pisulewski, P., Mrozikiewicz, M., & Bobkiewicz-Kozlowska, T. (2017). Peruvian Maca (Lepidium peruvianum) - III: The Effects of Cultivation Altitude on Phytochemical and Genetic Differences in the Four Prime Maca Phenotypes. International journal of biomedical science : IJBS, 13(2), 58–73.

Meissner H.O., Mscisz A., Kedzia B., et al. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically Synonymous?
International Journal of Biomedical Science, Mar. 2015: Vol. 11, No. 1. 1-15.

Ruiz-luna AC, Salazar S, Aspajo NJ, Rubio J, Gasco M, Gonzales GF. Lepidium meyenii (Yellow Maca) increases litter size in normal adult female mice. Reproductive Biology and Endocrinology 2005; 3:16.

Uchiyama F, Jikyo T, Takeda R, Ogata M. Lepidium meyenii (Maca) enhances the serum levels of luteinising hormone (LH) in female rats. Journal of Ethnopharmacology. 2014;151(2):897-902.

Harnly J., Geng P., Sun J., Chen P., Gafner S., Stewart J., Frame J., Meissner H.O. (2018).

Chemical and genetic characterization of Maca (Lepidium meyenii synonym Lepidium peruvianum)

Meissner H.O., Lijia Xu, Wenting Wan, Fan Yi. (2019).

Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii)

Characterization of Maca (Lepidium meyenii/Lepidium peruvianum) Using a Mass Spectral Fingerprinting, Metabolomic Analysis, and Genetic Sequencing Approach

Planta Med. 2020 Jul;86(10):674-685. doi: 10.1055/a-1161-0372. Epub 2020 May 20.

Ping Geng, Jianghao Sun, Pei Chen, Eric Brand, James Frame, Henry Meissner, Jeremy Stewart, Stefan Gafner, Stephanie Clark, Jesse Miller, James Harnly

Tarabasz D, Szczeblewski P, Laskowski T, Płaziński W, Baranowska-Wójcik E, Szwajgier D, Kukula-Koch W, Meissner HO. The Distribution of Glucosinolates in Different Phenotypes of Lepidium peruvianum and Their Role as Acetyl- and Butyrylcholinesterase Inhibitors-In Silico and In Vitro Studies. Int J Mol Sci. 2022 Apr 27;23(9):4858. doi: 10.3390/ijms23094858. PMID: 35563248; PMCID: PMC9101689.

Ross K. Improvements in Premenstrual Syndrome, Primary Dysmenorrhea, and Menorrhagia with Natural Therapies: A Case Report. Curr Res Cmpl Alt Med. 2023;7: 207. doi.org/10.29011/2577-2201.100207.

Minich DM, Ross K, Frame J, Fahoum M, Warner W, Meissner HO. Not All Maca Is Created Equal: A Review of Colors, Nutrition, Phytochemicals, and Clinical Uses. Nutrients. 2024;16(4):530. Published 2024 Feb 14.

Gonzales GF., Cordova A., Vega K., et al. Effect of Lepidium meyenii (Maca) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men.
Andrologia. 2002; 34:367-72.

Gonzales GF., Cordova A., Vega K., et al. Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enhancing properties, on serum reproductive hormone levels in adult
healthy men.
J Endocrinol. 2003; 176: 163–8.

Gonzales GF., Vanessa Vasquez, Daniella Rodriguez, Carmen Maldonado, Juliet Mormontoy, Jimmy Portella, Monica Pajuelo, León Villegas, Manuel Gasco, P.P. Mathur Effect of two different extracts of red maca in male rats with testosterone-induced prostatic hyperplasia. 2007; Vol. 9, No. 2 p. 245-51

Gonzales GF, Gasco M., A Córdova, A Chung, J Rubio and L Villegas Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats 1: Asian J Androl. 2001 Sep; 3(3):231-3

Gonzales GF., Cordova A., Gonzales C., et al. Lepidium meyenii (Maca) improved semen parameters in adult men. Asian J Androl. 2002; 3:301–3.

Gonzales GF., Gasco M., Cordova A., et al. Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats acutely exposed to high altitude (4340 m). J Endocrinol. 2004; 180:87–95.

Basic & Clinical Pharmacology & Toxicology. 2005; Vol. 97, Supp l (1): 48.

Meissner H.O., Kedzia B., Mrozikiewicz P.M., Mscisz A. Short and Long-Term Physiological Responses of Male and Female Rats to Two Dietary levels of Pre-Gelatinized Maca (Lepidium peruvianum Chacon).
International Journal of Biomedical Science. 2006; 1 (2): 61-78.2006 Vol. 2, No. 1. 13–28.

Meissner, Henry. (2019). Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii) Meissner HXu LWan WYi F Phytochemistry Letters 2019 vol: 31 pp: 208-216. Phytochemistry Letters. 31. 208-216. 10.1016/j.phytol.2019.04.011.

Meissner H.O., Mscisz A., Mrozikiewicz P.M., et al. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes.
International Journal of Biomedical Science, Sept. 2015. Vol. 11, No. 3. 131-45

Meissner, H.O., Mscisz, A., Piatkowska, E., Baraniak, M., Mielcarek, S., Kedzia, B., Holderna-Kedzia, E., & Pisulewski, P. (2016). Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations. International journal of biomedical science : IJBS, 12(1), 9–24.

Meissner H. O., Mscisz A., Baraniak M., Piatkowska E., Pisulewski P., Mrozikiewicz M., & Bobkiewicz-Kozlowska T. (2017). Peruvian Maca (Lepidium peruvianum) - III: The Effects of Cultivation Altitude on Phytochemical and Genetic Differences in the Four Prime Maca Phenotypes. International journal of biomedical science : IJBS, 13(2), 58–73.

Meissner H.O., Mscisz A., Kedzia B., et al. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically Synonymous?
International Journal of Biomedical Science, Mar. 2015: Vol. 11, No. 1. 1-15.

Harnly J., Geng P., Sun J., Chen P., Gafner S., Stewart J., Frame J., Meissner H.O. (2018).

Chemical and genetic characterization of Maca (Lepidium meyenii synonym Lepidium peruvianum)

Meissner H.O., Lijia Xu, Wenting Wan, Fan Yi. (2019).

Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii)

Characterization of Maca (Lepidium meyenii/Lepidium peruvianum) Using a Mass Spectral Fingerprinting, Metabolomic Analysis, and Genetic Sequencing Approach

Planta Med. 2020 Jul;86(10):674-685. doi: 10.1055/a-1161-0372. Epub 2020 May 20.

Ping Geng, Jianghao Sun, Pei Chen, Eric Brand, James Frame, Henry Meissner, Jeremy Stewart, Stefan Gafner, Stephanie Clark, Jesse Miller, James Harnly

Tarabasz D, Szczeblewski P, Laskowski T, Płaziński W, Baranowska-Wójcik E, Szwajgier D, Kukula-Koch W, Meissner HO. The Distribution of Glucosinolates in Different Phenotypes of Lepidium peruvianum and Their Role as Acetyl- and Butyrylcholinesterase Inhibitors-In Silico and In Vitro Studies. Int J Mol Sci. 2022 Apr 27;23(9):4858. doi: 10.3390/ijms23094858. PMID: 35563248; PMCID: PMC9101689.

Deanna M. Minich ,Melanie Henning, Catherine Darley, Mona Fahoum, Corey B. Schuler, and James Frame. Is Melatonin the “Next Vitamin D”?: A Review of Emerging Science, Clinical Uses, Safety, and Dietary Supplements. Nutrients 2022, 14(19), 3934.Text

Wirginia Kukula-Koch, Dominik Szwajgier, Katarzyna Gaweł-Bęben, Marcelina Strzępek-Gomółka, Kazimierz Głowniak, and Henry O. Meissner. Is Phytomelatonin Complex Better Than Synthetic Melatonin? The Assessment of the Antiradical and Anti-Inflammatory Properties. Molecules. 2021 Oct; 26(19): 6087.

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