Published Clinical Research Articles

Maca-GO White Paper – Clinical Effects of a Proprietary, Standardized, Concentrated, Organic Lepidium peruvianum Formulation (Maca-GO) as an Alternative to HRT by Ronald Carter, M.D.

Toru Tabei, M.D.Ph.D. Recent Topics in Western Countries: Effect of Maca-GO upon Menopausal Symptoms

Journal of The Japan Menopause Society April 2010. Vol. 18, No. 1, pp. 49-56

Meissner H.O., Mrozikiewicz P., Bobkiewicz-Kozlowska T., et al. Hormone-balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon: (Part I.) Biochemical and Pharmacodynamic Study on Maca using Clinical Laboratory Model on Ovariectomized Rats.
International Journal of Biomedical Science 2006: Vol. 2, No. 3. 260-72

Meissner H.O., Mscisz A., Reich-Bilinska H., et al. Hormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon): (II) Physiological & symptomatic responses of early-postmenopausal women to standardized doses of Maca in Double Blind, Randomized, Placebo-Controlled, Multi-Centre Clinical Study.
International Journal of Biomedical Science, Dec. 2006: Vol. 2 No. 4, 360–74.

Meissner H.O., Mscisz A., Reich-Bilinska H., et al. Hormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon): (III) Clinical responses of early-postmenopausal women to Maca in double blind, randomized, Placebo-controlled, crossover configuration, outpatient study.
International Journal of Biomedical Science., Dec. 2006: Vol. 2 No. 4, 375–94.

Meissner, Henry. (2019). Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii) Meissner HXu LWan WYi F Phytochemistry Letters 2019 vol: 31 pp: 208-216. Phytochemistry Letters. 31. 208-216. 10.1016/j.phytol.2019.04.011.

Meissner H.O., Reich-Bilinska H., Mrozikiewicz P., et al. Hormone-balancing and Pharmacological Effects of Therapeutic Doses of Lepidium peruvianum (Maca-GO) in Postmenopausal Women.
Menopause. 2005; Vol. 12, No. 6. p. 813.

Meissner H.O., Kapczynski W., Mscisz A., Lutomski J. Use of Gelatinized Maca (Lepidium peruvianum) in Early Postmenopausal Women – a Pilot Study.
International Journal of Biomedical Science. 2005; Vol. 1, No. 1. p. 33-45.

Meissner H.O., Reich-Bilinska H., Kedzia B., Mscisz A. Pre-Gelatinised Maca (Lepidium peruvianum Chacon) As Non-Hormonal Herbal Remedy to Treat Menopausal Symptoms in
Pre- and Post-Menopausal Women.

Meissner H.O., Mscisz A., Kedzia B., et al. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically Synonymous? International Journal of Biomedical Science, Mar. 2015: Vol. 11, No. 1. 1-15

Meissner H.O., Kedzia B., Mrozikiewicz P.M., Mscisz A. Short and Long-Term Physiological Responses of Male and Female Rats to Two Dietary levels of Pre-Gelatinized Maca (Lepidium peruvianum Chacon).
International Journal of Biomedical Science. 2006; 1 (2): 61-78.2006 Vol. 2, No. 1. 13–28.

Meissner H.O., Mscisz A., Mrozikiewicz P.M., et al. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes.
International Journal of Biomedical Science, Sept. 2015. Vol. 11, No. 3. 131-45

Meissner H.O., Mscisz A., Piatkowska E., Baraniak M., Mielcarek S., Kedzia B., Holderna-Kedzia E., & Pisulewski P. (2016). Peruvian M,aca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations. International journal of biomedical science : IJBS, 12(1), 9–24.

Meissner H.O., Mscisz A., Baraniak M., Piatkowska E., Pisulewski P., Mrozikiewicz M., & Bobkiewicz-Kozlowska T. (2017). Peruvian Maca (Lepidium peruvianum) - III: The Effects of Cultivation Altitude on Phytochemical and Genetic Differences in the Four Prime Maca Phenotypes. International journal of biomedical science : IJBS, 13(2), 58–73.

Harnly J., Geng P., Sun J., Chen P., Gafner S., Stewart J., Frame J., Meissner H.O. (2018).

Chemical and genetic characterization of Maca (Lepidium meyenii synonym Lepidium peruvianum)

Meissner H.O., Lijia Xu, Wenting Wan, Fan Yi. (2019).

Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii)

Maca-GO White Paper – Clinical Effects of a Proprietary, Standardized, Concentrated, Organic Lepidium peruvianum Formulation (Maca-GO) as an Alternative to HRT by Ronald Carter, M.D.

Meissner H.O., Reich-Bilinska H., Mscisz A., Kedzia B. Therapeutic effect of Lepidium peruvianum Chacon (Pre-Gelatinised Maca) used as a non-hormonal alternative to HRT in
Peri-menopausal women - Clinical Pilot Study.
International Journal of Biomedical Science 2006: Vol. 2, No. 2. 143-59.

Meissner, Henry. (2019). Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii) Meissner HXu LWan WYi F Phytochemistry Letters 2019 vol: 31 pp: 208-216. Phytochemistry Letters. 31. 208-216. 10.1016/j.phytol.2019.04.011.

Meissner H.O., Reich-Bilinska H., Kedzia B., Mscisz A. Pre-Gelatinised Maca (Lepidium peruvianum Chacon) As Non-Hormonal Herbal Remedy to Treat Menopausal Symptoms in
Pre- and Post-Menopausal Women.
Basic & Clinical Pharmacology & Toxicology. 2005; Vol. 97, Supp l (1): 48.

Meissner H.O., Kapczynski W., Mscisz A., Lutomski J. Use of Gelatinized Maca (Lepidium peruvianum) in Early Postmenopausal Women – a Pilot Study. International Journal of Biomedical Science. 2005; 1 (1): 33-45.

Meissner H.O., Kedzia B., Mrozikiewicz P.M., Mscisz A. Short and Long-Term Physiological Responses of Male and Female Rats to Two Dietary levels of Pre-Gelatinized Maca (Lepidium peruvianum Chacon).
International Journal of Biomedical Science. 2006; 1 (2): 61-78.2006 Vol. 2, No. 1. 13–28.

Meissner H.O., Mscisz A., Mrozikiewicz P.M., et al. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes.
International Journal of Biomedical Science, Sept. 2015. Vol. 11, No. 3. 131-45

Meissner, H.O., Mscisz, A., Piatkowska, E., Baraniak, M., Mielcarek, S., Kedzia, B., Holderna-Kedzia, E., & Pisulewski, P. (2016). Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations. International journal of biomedical science : IJBS, 12(1), 9–24.

Meissner, H. O., Mscisz, A., Baraniak, M., Piatkowska, E., Pisulewski, P., Mrozikiewicz, M., & Bobkiewicz-Kozlowska, T. (2017). Peruvian Maca (Lepidium peruvianum) - III: The Effects of Cultivation Altitude on Phytochemical and Genetic Differences in the Four Prime Maca Phenotypes. International journal of biomedical science : IJBS, 13(2), 58–73.

Toru Tabei, M.D.Ph.D. Recent Topics in Western Countries: Effect of Maca-GO upon Menopausal Symptoms
Journal of The Japan Menopause Society April 2010. Vol. 18, No. 1, pp. 49-56

Meissner H.O., Mscisz A., Kedzia B., et al. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically Synonymous?
International Journal of Biomedical Science, Mar. 2015: Vol. 11, No. 1. 1-15.

Harnly J., Geng P., Sun J., Chen P., Gafner S., Stewart J., Frame J., Meissner H.O. (2018).

Chemical and genetic characterization of Maca (Lepidium meyenii synonym Lepidium peruvianum)

Meissner H.O., Lijia Xu, Wenting Wan, Fan Yi. (2019).

Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii)

Maca-GO White Paper – Clinical Effects of a Proprietary, Standardized, Concentrated, Organic Lepidium peruvianum Formulation (Maca-GO) as an Alternative to HRT by Ronald Carter, M.D.

Meissner, Henry. (2019). Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii) Meissner HXu LWan WYi F Phytochemistry Letters 2019 vol: 31 pp: 208-216. Phytochemistry Letters. 31. 208-216. 10.1016/j.phytol.2019.04.011.

Meissner H.O., Reich-Bilinska H., Kedzia B., Mscisz A. Pre-Gelatinised Maca (Lepidium peruvianum Chacon) As Non-Hormonal Herbal Remedy to Treat Menopausal Symptoms in
Pre- and Post-Menopausal Women.

Meissner H.O., Kedzia B., Mrozikiewicz P.M., Mscisz A. Short and Long-Term Physiological Responses of Male and Female Rats to Two Dietary levels of Pre-Gelatinized Maca (Lepidium peruvianum Chacon).
International Journal of Biomedical Science. 2006; 1 (2): 61-78.2006 Vol. 2, No. 1. 13–28.

Meissner H.O., Mscisz A., Mrozikiewicz P.M., et al. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes.
International Journal of Biomedical Science, Sept. 2015. Vol. 11, No. 3. 131-45

Meissner, H.O., Mscisz, A., Piatkowska, E., Baraniak, M., Mielcarek, S., Kedzia, B., Holderna-Kedzia, E., & Pisulewski, P. (2016). Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations. International journal of biomedical science : IJBS, 12(1), 9–24.

Meissner, H. O., Mscisz, A., Baraniak, M., Piatkowska, E., Pisulewski, P., Mrozikiewicz, M., & Bobkiewicz-Kozlowska, T. (2017). Peruvian Maca (Lepidium peruvianum) - III: The Effects of Cultivation Altitude on Phytochemical and Genetic Differences in the Four Prime Maca Phenotypes. International journal of biomedical science : IJBS, 13(2), 58–73.

Meissner H.O., Mscisz A., Kedzia B., et al. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically Synonymous?
International Journal of Biomedical Science, Mar. 2015: Vol. 11, No. 1. 1-15.

Ruiz-luna AC, Salazar S, Aspajo NJ, Rubio J, Gasco M, Gonzales GF. Lepidium meyenii (Yellow Maca) increases litter size in normal adult female mice. Reproductive Biology and Endocrinology 2005; 3:16.

Uchiyama F, Jikyo T, Takeda R, Ogata M. Lepidium meyenii (Maca) enhances the serum levels of luteinising hormone (LH) in female rats. Journal of Ethnopharmacology. 2014;151(2):897-902.

Harnly J., Geng P., Sun J., Chen P., Gafner S., Stewart J., Frame J., Meissner H.O. (2018).

Chemical and genetic characterization of Maca (Lepidium meyenii synonym Lepidium peruvianum)

Meissner H.O., Lijia Xu, Wenting Wan, Fan Yi. (2019).

Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii)

Gonzales GF., Cordova A., Vega K., et al. Effect of Lepidium meyenii (Maca) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men.
Andrologia. 2002; 34:367-72.

Gonzales GF., Cordova A., Vega K., et al. Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enhancing properties, on serum reproductive hormone levels in adult
healthy men.
J Endocrinol. 2003; 176: 163–8.

Gonzales GF., Vanessa Vasquez, Daniella Rodriguez, Carmen Maldonado, Juliet Mormontoy, Jimmy Portella, Monica Pajuelo, León Villegas, Manuel Gasco, P.P. Mathur Effect of two different extracts of red maca in male rats with testosterone-induced prostatic hyperplasia. 2007; Vol. 9, No. 2 p. 245-51

Gonzales GF, Gasco M., A Córdova, A Chung, J Rubio and L Villegas Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats 1: Asian J Androl. 2001 Sep; 3(3):231-3

Gonzales GF., Cordova A., Gonzales C., et al. Lepidium meyenii (Maca) improved semen parameters in adult men. Asian J Androl. 2002; 3:301–3.

Gonzales GF., Gasco M., Cordova A., et al. Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats acutely exposed to high altitude (4340 m). J Endocrinol. 2004; 180:87–95.

Basic & Clinical Pharmacology & Toxicology. 2005; Vol. 97, Supp l (1): 48.

Meissner H.O., Kedzia B., Mrozikiewicz P.M., Mscisz A. Short and Long-Term Physiological Responses of Male and Female Rats to Two Dietary levels of Pre-Gelatinized Maca (Lepidium peruvianum Chacon).
International Journal of Biomedical Science. 2006; 1 (2): 61-78.2006 Vol. 2, No. 1. 13–28.

Meissner, Henry. (2019). Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii) Meissner HXu LWan WYi F Phytochemistry Letters 2019 vol: 31 pp: 208-216. Phytochemistry Letters. 31. 208-216. 10.1016/j.phytol.2019.04.011.

Meissner H.O., Mscisz A., Mrozikiewicz P.M., et al. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes.
International Journal of Biomedical Science, Sept. 2015. Vol. 11, No. 3. 131-45

Meissner, H.O., Mscisz, A., Piatkowska, E., Baraniak, M., Mielcarek, S., Kedzia, B., Holderna-Kedzia, E., & Pisulewski, P. (2016). Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations. International journal of biomedical science : IJBS, 12(1), 9–24.

Meissner H. O., Mscisz A., Baraniak M., Piatkowska E., Pisulewski P., Mrozikiewicz M., & Bobkiewicz-Kozlowska T. (2017). Peruvian Maca (Lepidium peruvianum) - III: The Effects of Cultivation Altitude on Phytochemical and Genetic Differences in the Four Prime Maca Phenotypes. International journal of biomedical science : IJBS, 13(2), 58–73.

Meissner H.O., Mscisz A., Kedzia B., et al. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically Synonymous?
International Journal of Biomedical Science, Mar. 2015: Vol. 11, No. 1. 1-15.

Harnly J., Geng P., Sun J., Chen P., Gafner S., Stewart J., Frame J., Meissner H.O. (2018).

Chemical and genetic characterization of Maca (Lepidium meyenii synonym Lepidium peruvianum)

Meissner H.O., Lijia Xu, Wenting Wan, Fan Yi. (2019).

Glucosinolates profiles in Maca phenotypes cultivated in Peru and China (Lepidium peruvianum syn. L. meyenii)

Melke, J., Goubran Botros, H., Chaste, P., Betancur, C., Nygren, G., Anckarsäter, H., Rastam, M., Ståhlberg, O., Gillberg, I. C., Delorme, R., Chabane, N., Mouren-Simeoni, M. C., Fauchereau, F., Durand, C. M., Chevalier, F., Drouot, X., Collet, C., Launay, J. M., Leboyer, M., Gillberg, C., … Bourgeron, T. (2008). Abnormal melatonin synthesis in autism spectrum disorders. Molecular psychiatry, 13(1), 90–98. https://doi.org/10.1038/sj.mp.4002016

Arendt, J. (1994) Human responses to light and melatonin, pp 439-442 in: “Advances in Pineal Research”, Vol 8, Eds: M. Moller and P. Pevet, J. Libbey, London.

Arendt, J. (1995) Significance of melatonin in humans, pp 165-171 in: “The Pineal Gland and its Hormones” Eds: Fraschini, F., Reiter, R.J. and Stankov, B., Plenum Press, New York.

Armstrong, S. M. (1991) Treatment of sleep disorders by melatonin administration, pp 263-274 in: “Advances in Pineal Research,” Vol.6, Eds: A. Foldes and R. J. Reiter, John Libbey, London.

Balzer, I. and Hardeland, R. (1996) Melatonin in algae and higher plants - possible roles as a phytohormone and antioxidant. Botanica Acta 109: 180-183.

Blask, D.E. and Wilson, S.T. (1995) Melatonin action on human breast cancer cells: involvement of glutathione metabolism and the redox environment. pp 209-217 in: “The Pineal Gland
and its Hormones” Eds: Fraschini, F., Reiter, R.J. and Stankov, B., Plenum Press, New York.

Cagnoni, M.L., Lombardi, A., Cerinic, et al. (1995) Melatonin for treatment of chronic refractory sarcoidosis, Lancet, 346 (8984): 1229-1230.

Chan, T.Y. and Tang, P.L. (1995) Effect of melatonin on the maintenance of cholesterol homeostasis in the rat, Endocrine Res. 21: 681-696.

Chaste P.et al. Genetic variations of the melatonin pathway in patients with attention-deficit and hyperactivity disorders. J Pineal Res. 2011 Apr 27. [Epub]

Dubbels, R., Reiter, R.J., Klenke, E., Goebel, A., Schnakenberg, E., Ehlers, C., Schiwara, H.W. and Schloot, W. (1995) Melatonin in edible plants identified by radioimmunoassay and by
high performance liquid chromatography-mass spectrometry, J. Pineal Res. 18: 28-31.

Escames G, et al. The role of mitochondria in brain aging and the effects of melatonin.CurrNeuropharmacol. 2010 Sep;8(3):182-93.

Folkard, S., Arendt, J. and Clark, M. (1993) Can melatonin improve shiftworkers tolerance of the night shift? Some preliminary findings, Quoted in Arendt, J (1994) Human responses to
light and melatonin Advances in Pineal Research, Vol 8, Eds: M. Moller and P. Pevet, J. Libbey, London.

Frye RE. Melatonin in autism spectrum disorders: a systematic review and meta-analysis. Dev Med Child Neurol. 2011 Apr 19. doi: 10.1111/j.1469-8749.2011.03980.x. [Epub]

Guardiola-Lemaitre, B. (1994) Melatonin agonist/antagonist: from the receptor to therapeutic applications, in: “Advances in Pineal Research”, Vol 8, Eds: M. Moller and P. Pevet,
pp 333-348, J. Libbey, London.

Hattori, A., Migitaka, H., Iigo, M., Itoh, M., Yamamoto, K., Ohtani-Kaneko, R., Hara, M., Suzuki, T. and Reiter, R.J. (1995) Identification of melatonin in plants and its effects on plasma
melatonin levels and binding to melatonin receptors in vertebrates, Biochem. Mol. Biol. Int. 35: 627-634.

Huber CG. The role of melatonin in glaucoma: implications concerning pathophysiological relevance and therapeutic potential. J Pineal Res. 2011 Jan;50(1):1-7.

Iguchi, H. et al. Age-Dependent Reduction in Serum Melatonin Concentrations in Healthy Human Subjects. The Journal of Clinical Endocrinology & Metabolism. July 1, 1982 vol. 55 no. 1 27-29.

Jean‐Louis, G. , Gizycki, H. and Zizi, F. (1998), Melatonin effects on sleep, mood, and cognition in elderly with mild cognitive impairment. Journal of Pineal Research, 25: 177-183. doi:10.1111/j.1600-079X.1998.tb00557.x

Kaczor, T. An Overview of Melatonin and Breast Cancer. Natural Medicine Journal 2010 Feb.[Epub]

Knutsson, A. Health disorders of shift worker. Occupational Medicine 2003;53:103–10

Kumar A, SharmaSS.Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF-κB and Nrf2 cascades. J Pineal Res. 2011 Mar;50(2):124-31.

Lewy AJ, Low, but not high, doses of melatonin entrained a free-running blind person with a long circadian period. Chronobiol Int. 2002 May;19(3):649-58.

Lissoni, P., Barni, S., Fossati, V.,Ardizzoia, A., et al. (1995) A randomized study of neuroimmunotherapy with low dose subcutaneous interleukin-2 plus melatonin compared to
supportive care alone in patients with untreatable metastatic solid tumour, Support Care Cancer, 3: 194-197.

Maestroni, G.J.M., Conti, A. et al (1994) pp 73-81 in: “Advances in Pineal Research” vol 7, Eds: Maestroni, G.J.M., Conti, A & Reiter, R.J. John Libbey, London.

Melatonin treatment improves blood pressure, lipid profile, and parameters of oxidative stress in patients with metabolic syndrome. J Pineal Res. 2011 Apr;50(3):261-6. Epub 2010 Dec 8.

Nagtegaal.E., Smits, M., Swart,W., van der Meer, G., and Kerkhof, G.(1995) Melatonin secretion and coronary heart disease, Lancet 346 (8985): 1299.

Oaknin-Bendahan, S, Anis, Y, Nir, et al.(1995) Effects of long-term administration of melatonin and a putative antagonist on the ageing rat, Neuroreport, 6: 785-8.

Ochoa, J. J., Díaz‐Castro, J. , Kajarabille, N. , García, C. , Guisado, I. M., De Teresa, C. and Guisado, R. (2011), Melatonin supplementation ameliorates oxidative stress and inflammatory signaling induced by strenuous exercise in adult human males. Journal of Pineal Research, 51: 373-380. doi:10.1111/j.1600-079X.2011.00899.x

Parkes, J.D. (1995) Melatonin and sleep, pp 183-198 in: “The Pineal Gland and its Hormones” Eds: Fraschini, F., Reiter, R.J. and Stankov, B., Plenum Press, NY.

Pierpaoli, W., Dall’Ara, A., Pedrinis, E., and Regelson, W. (1991) The pineal control of ageing. The effects of melatonin and pineal grafting on the survival of older mice, Ann. N.Y. Acad.
Sci, 621: 291-313.

Furio, A.M., Brusco, L.I. and Cardinali, D.P. (2007), Possible therapeutic value of melatonin in mild cognitive impairment: a retrospective study. Journal of Pineal Research, 43: 404-409. doi:10.1111/j.1600-079X.2007.00491.x

Potential of melatonin to treat or prevent age-related macular degeneration through stimulation of telomerase activity.Med Hypotheses. 2011 Jan;76(1):79-85

Salvatore Aversa, Salvatore Pellegrino, Ignazio Barberi, Russel J. Reiter & Eloisa Gitto (2012) Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period, The Journal of Maternal-Fetal & Neonatal Medicine, 25:3, 207-221, DOI: 10.3109/14767058.2011.573827

Powell, D. W., (2004) pp 39-42 Endocrinology & Naturopathic Therapies 6th Edition

Olcese, J.M., Cao, C., Mori, T., Mamcarz, M.B., Maxwell, A., Runfeldt, M.J., Wang, L., Zhang, C., Lin, X., Zhang, G. and Arendash, G.W. (2009), Protection against cognitive deficits and markers of neurodegeneration by long‐term oral administration of melatonin in a transgenic model of Alzheimer disease. Journal of Pineal Research, 47: 82-96. doi:10.1111/j.1600-079X.2009.00692.x

Jean‐Louis, G., von, Gizycki, H. and Zizi, F. (1998), Melatonin effects on sleep, mood, and cognition in elderly with mild cognitive impairment. Journal of Pineal Research, 25: 177-183. doi:10.1111/j.1600-079X.1998.tb00557.x

Srinivasan, V., Spence, D. W., Pandi-Perumal, S. R., Brown, G. M., & Cardinali, D. P. (2011). Melatonin in mitochondrial dysfunction and related disorders. International journal of Alzheimer's disease, 2011, 326320. https://doi.org/10.4061/2011/326320

Robinson, W.A., Dreiling, L., Gonzalez, R. and Balmer, C. (1995) Treatment of human metastatic malignant melanoma with highdose oral melatonin, pp 219-225 in: “The Pineal Gland
and its Hormones” Eds: Fraschini, F., Reiter, R.J. and Stankov, B., Plenum Press, New York.

The Sleep Disorders Inventory: an instrument for studies of sleep disturbance in persons with Alzheimer's disease.J Sleep Res. 2003 Dec;12(4):331-7.

Vijayalaxmi, Reiter, et al (1995) Marked reduction of radiation-induced micronuclei in human blood lymphocytes pretreated with melatonin, Radiation Res. 143: 102 - 106.

Wetterberg, L. (1995) Seasonal affective disorder, melatonin and light, pp 199-208 in: “The Pineal Gland and its Hormones” Eds: Fraschini, F., Reiter, R.J. and Stankov, B., Plenum Press, New York

Zhdanova IV, et al. Effects of a low dose of melatonin on sleep in children with Angelman syndrome. J PediatrEndocrinolMetab. 1999 Jan-Feb;12(1):57-67.

Zhdanova IV, et al. Melatonin Treatment for Age-Related Insomnia. J ClinEndocrinolMetab, October 2001, 86(10):4727–4730

Solomon Habtemariam, Maria Daglia, Antoni Sureda, Zeliha Selamoglu, Mehmet Fuat Gulhan and Seyed Mohammad Nabavi, “Melatonin and Respiratory Diseases: A Review”, Current Topics in Medicinal Chemistry (2017) 17: 467. https://doi.org/10.2174/1568026616666160824120338

P. R. Cheeke (1983). Biological Properties and Nutritional Significance of Legume Saponins. Chapter 21, in Leaf Proteins (L. Telek, ed.), A.V.I. Publ. Co., Westport, p.396-414.

H. O. Meissner, R. Carlson and C. Tragardh, (1980). Isolation and purification of proteins from green vegetation for direct human consumption. In: "Food Process Engineering". (P. Linko, Y. Maiki, J. Olkku, Editors) pp. 864-870. Applied Science Publishers Ltd, London.

H. O. Meissner (1989). Commercial Applications of Leaf Protein Research - three faces of industrial leaf fractionation: resources - operation and marketing.. LEAFPRO-89, Pisa, Perugia, Vitterbo-Italy. Italian Journal of Food Science. 1989; p. 360-365.

N.W. Pirie (1987). Leaf Protein and its by-products in human and animal nutrition. London, Cambridge University Press.

H. O. Meissner (1983). Protein Concentrates from Herbage and their Fractionation into Feed- and Food-grade Products. Chapter 15, in: Leaf Proteins (L. Telek, ed.), A.V.I. Publ. Co., Westport, p.437-466.

TGA, Department of Health and Aging, Australian Government. Pure Alfalfa Extract Tablets Medicago sativa (750mg): ARTG registration/listing No: 83132. Supporting evidence for listing of a Therapeutic Preparation. (Canberra, 21 June 2002).