Femmenessence®

MacaPause® 3-Box Subscription

For Postmenopause

360 Capsules | 3-Month Supply

5.0/5.0

1 10

Femmenessence®

MacaPause® 3-Box Subscription

For Postmenopause

360 Capsules | 3-Month Supply

5.0/5.0

1-Box One-Time Purchase
$36.99

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3-Box Subscribe & Save
$110.97 $88.78
  • $29.59/per box
  • Ships Every 3 Months
  • Free Shipping, Flexible Delivery
  • Cancel or Pause Anytime

Femmenessence® MacaPause® is the first natural product with published double-blind, placebo-controlled human clinical trials showing statistically significant effects on postmenopausal women’s hormones. Instead of introducing hormones into the body, Femmenessence works by nourishing the endocrine system to support the body’s own hormone production.

 

Benefits of MacaPause®:

  • 84% of women reported relief from menopausal symptoms within 2 days to 8 weeks (average 21 days).*
  • This number went up to 95% with guidance from our Medical Team.*
  • Supports relief from all menopausal symptoms, including: hot flashes, night sweats, sleep changes and mood fluctuations.*
  • Clinically shown to support bone density, brain health, cholesterol and healthy body weight.*
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Femmenessence MacaPause For Postmenopause 3-Box Subscription
Femmenessence®
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MacaPause® 3-Box Subscription
How It Works Clinical Research Ingredients & Sourcing Community Reviews FAQ
HOW IT WORKS

How Femmenessence® Works to Support Your Hormones, Naturally.

Dr. Deanna Minich, PHD, CNS, IFMCP

Chief Science Officer, Symphony Natural Health

Targets the Root Cause of Menopause

In menopause, communication between the brain and ovaries naturally slows, influencing how hormones are produced and balanced. Femmenessence supports the endocrine system—the HPTAO axis—the body’s hormonal communication network that regulates mood, metabolism, energy and more.*

Supports Your Body’s Own Natural Hormone Production

Instead of introducing synthetic or plant-based hormones, Femmenessence nourishes the body’s natural ability to produce and regulate its own. This means it doesn’t just increase low hormones—it also helps reduce those that are out of balance, supporting your body in finding its optimal rhythm.*

Supports Longevity, Not 
Just Symptoms

Published clinical research shows that Femmenessence not only supports hormonal balance, but also positively impacts key biomarkers for heart, bone and brain health, which are affected by hormonal changes, helping women feel better today while supporting long-term vitality.*

Delivers Real Results Within 1-2 Boxes

In published, double-blind, placebo-controlled clinical trials, 84% of women experienced improvements within 2 days to 8 weeks (on average, 21 days). When guided by our Medical Team, success rates rose to 95%—with personalized guidance on simple factors like dosage, hydration and nutrition making all the difference.*

From Symptom Relief to Longevity: Hormone Balance is the Key 

Supports Symptom Relief:

Hormone Balance*

Dryness & Desire*

Hot Flashes & Night Sweats*

Mood Swings*

Promotes Longevity:

Heart Health*

Bone Health*

Brain Health*

Energy & Sleep*

Beauty From The Inside Out:

Hair, Skin & Nail Health*

CLINICAL RESULTS

No More Empty Promises: We Lead with Clinical Evidence & Proof

Most brands talk about balance. Few can prove it. Femmenessence® MacaPause® is one of the few natural products with published, double-blind, placebo-controlled human clinical trials in postmenopausal women, showing statistically significant improvements in hormones, symptoms and overall well-being.*

Kupperman's Index +

The gold standards for measuring menopausal well-being—tracking real experiences such as hot flashes, sleep, mood and energy.*

Kupperman’s Menopausal Index

Menopause isn’t just about hormone levels—it’s about how you feel day to day.

To measure meaningful change, researchers used the Kupperman Menopausal Index and the Greene Climacteric Scale, two validated tools that evaluate symptoms such as hot flashes, night sweats, sleep quality, mood, nervousness and energy levels. These scales help capture what matters most: women’s lived experiences.

In published clinical studies, 84% of postmenopausal women reported symptom relief, often within 2 days to 8 weeks, with many noticing improvements around 21 days.*

These symptom changes occurred during the same study period in which women also showed shifts in key hormonal markers, demonstrating broader support for overall well-being.*

Women in the studies commonly reported:

  • Relief from symptoms such as hot flashes, night sweats and disrupted sleep*
  • More stable mood and emotional well-being*
  • Improved energy and day-to-day vitality*
  • A clear effect demonstrated through placebo crossover design: women improved on Femmenessence, worsened on placebo, and improved again when switched back.*
  • 95% success rate when women were supported by our Medical Team during real-world use*

Publication:

Estradiol +

Estradiol is the primary form of estrogen—key for temperature, mood, bone, and heart health. After menopause, levels decline, which can contribute to many common symptoms women experience.*

Estradiol

In published double-blind, placebo-controlled clinical trials on postmenopausal women, those taking Femmenessence® MacaPause® experienced a statistically significant increase in estradiol—over 200% on average in just two months—compared to placebo.*

This hormonal shift occurred during the same study period in which women also reported improvements in menopausal symptoms, as measured separately using validated symptom scales.*

Women commonly reported:

  • Fewer hot flashes and night sweats*
  • More stable mood and energy levels*
  • Improved sleep quality and reduced fatigue*
  • Support for overall well-being and vitality*

By supporting the body’s natural ability to regulate estradiol—rather than adding hormones—Femmenessence® MacaPause® helps support healthier hormonal communication during postmenopause.*

Publication:

FSH +

FSH—follicle-stimulating hormone—naturally rises after menopause as the ovaries produce fewer reproductive hormones. Elevated FSH is one of the clearest biological indicators that a woman has entered postmenopause.*

FSH

As women move into postmenopause, FSH levels increase significantly as the ovaries shift away from producing reproductive hormones.

In published double-blind, placebo-controlled clinical trials, postmenopausal women taking Femmenessence® MacaPause® experienced a statistically significant decrease in FSH—an average reduction of 34% within four months—compared to placebo.*

This hormonal shift occurred during the same study period in which women also reported improvements in menopausal symptoms, as measured separately using validated symptom scales.*

Women commonly reported:

  • Fewer hot flashes and night sweats*
  • More consistent energy and steadier mood*
  • Improved sleep and overall well-being*

By supporting the body’s natural ability to regulate FSH—rather than adding hormones—Femmenessence® MacaPause® helps support healthier hormonal communication during postmenopause.*

Publication:

Heart Health +

After menopause, changing hormone patterns can influence how the body manages cholesterol, circulation and other cardiovascular markers.*

Heart Health

After menopause, natural declines in estrogen can affect how the body regulates lipids such as HDL, LDL and triglycerides, as well as factors like blood pressure and weight. These shifts can influence overall cardiovascular markers, which in turn can affect how women feel day to day.

In published double-blind, placebo-controlled clinical trials, postmenopausal women taking Femmenessence® MacaPause® showed statistically significant improvements in several key cardiovascular markers, including*:

  • HDL (“good”) cholesterol*
  • LDL (“bad”) cholesterol*
  • Triglycerides*
  • Blood pressure and body weight*

These improvements occurred during the same study period in which women also reported benefits in energy, mood and overall well-being measured separately through validated symptom scales.*

By supporting healthy hormonal communication and overall physiological balance, Femmenessence MacaPause® helps support the systems that influence circulation and day-to-day vitality during postmenopause.*

Publication: 

Bone Health +

Hormonal shifts during postmenopause can influence bone density. Femmenessence supports healthy hormone communication, which plays a role in maintaining bone strength over time.*

Bone Health

After menopause, natural declines in estradiol can accelerate changes in bone density, influencing long-term skeletal health. In the MacaPause clinical trials, researchers evaluated whether supporting healthier hormonal balance could also influence bone density markers.

In a published, double-blind, placebo-controlled pilot study, postmenopausal women taking Femmenessence® MacaPause® showed positive changes in bone density markers—including improvements in total bone density and Z-scores—compared with placebo over 4 months.*

These findings reflect early evidence of broader physiological support observed during the same research period, when women also experienced improvements in hormone patterns and menopausal symptoms.*

Women in the study commonly showed:

  • Higher total bone density after four months on Femmenessence®*
  • Increased Z-scores compared to baseline*
  • Trends not observed in the placebo group

By supporting the body’s natural hormonal communication network, Femmenessence helps maintain the internal balance that influences bone health during postmenopause—supporting strength for the years ahead.*

Publication: 

Mood & Emotional Well-Being +

Menopause influences more than physical comfort—it can affect mood, clarity, sleep and how you respond to daily life.*

Mood, Focus & Emotional Well-Being

During postmenopause, natural changes in hormone levels can influence how women feel emotionally and mentally. Many women experience shifts in mood, energy, sleep patterns and overall sense of well-being during this stage.

In published double-blind, placebo-controlled clinical trials, postmenopausal women taking Femmenessence® MacaPause® reported statistically significant improvements in mood, energy and emotional well-being compared to placebo, as measured through validated symptom scales.*

These improvements occurred during the same study period in which women also experienced changes in other markers of menopausal health, showing a broader shift in day-to-day well-being.*

Women commonly reported:

  • Improved mood and emotional steadiness*
  • Better energy and overall vitality*
  • More restful sleep and reduced nervousness*

Femmenessence® MacaPause® contains a natural spectrum of amino acids and plant compounds—including macamides and macaenes—which support overall well-being and help maintain healthy communication throughout the body.*

Publication: 

Hair, Skin & Nail Health +

Hormonal changes during postmenopause can influence visible aspects of well-being, including hair, skin and nail appearance.*

Hair, Skin & Nail Health

During postmenopause, natural declines in estradiol can affect hydration, elasticity, and the appearance of hair, skin and nails. Many women notice changes such as dryness, thinning or reduced vitality during this stage.

In published double-blind, placebo-controlled clinical trials, postmenopausal women taking Femmenessence® MacaPause® reported visible improvements in hair thickness, skin vitality and nail strength after four months, compared to placebo.*

These appearance-related improvements occurred during the same study period in which women also reported benefits in mood, energy and overall well-being, as measured separately using validated symptom scales.*

Women in the study commonly reported:

  • Healthier-looking skin with improved vitality*
  • Stronger nails*
  • Thicker-feeling or more resilient hair*

By supporting the body’s natural hormonal communication, Femmenessence MacaPause® helps maintain the internal balance that contributes to visible vitality during postmenopause.*

Publication: 

Case Report: Surgical Menopause +

In a published case report, a woman experiencing symptoms following surgical menopause reported improvements in her well-being while using Femmenessence as part of a broader care plan.*

Case Report: Surgical Menopause

Surgical menopause occurs when the ovaries are removed—a procedure known as oophorectomy—resulting in an abrupt drop in hormones. This sudden change can lead to experiences such as hot flashes, night sweats, sleep disruption and emotional challenges.

While double-blind, placebo-controlled trials demonstrate that Femmenessence® MacaPause® supports groups of postmenopausal women, case reports offer insight into how individuals may experience its use during more complex or rapid transitions.

One published case described a 32-year-old woman who entered immediate menopause after hysterectomy and oophorectomy. She reported symptoms including hot flashes, night sweats, anxiousness, sleep disruption and mood fluctuations—commonly associated with surgical menopause.

Her care plan included:

  • Femmenessence® MacaPause®
  • A tailored nutrition plan
  • Nutrient supplementation
  • Lifestyle and wellness recommendations

Over eight weeks, she reported noticeable improvements in several of her symptoms, including fewer hot flashes, steadier mood and more restful sleep, as documented in the case report.*

It’s important to note that case reports describe the experience of a single individual and are not intended to predict outcomes for others. However, they offer meaningful context for understanding real-world use alongside clinical trial findings.*

The woman in this case report noted:

  • Fewer hot flashes and night sweats*
  • Improved sleep quality*
  • More stable mood and emotional well-being*
  • Support as part of a non-hormonal wellness approach*

Publication:

Learn More

Kupperman’s Menopausal Index

Menopause isn’t just about hormone levels—it’s about how you feel day to day.

To measure meaningful change, researchers used the Kupperman Menopausal Index and the Greene Climacteric Scale, two validated tools that evaluate symptoms such as hot flashes, night sweats, sleep quality, mood, nervousness and energy levels. These scales help capture what matters most: women’s lived experiences.

In published clinical studies, 84% of postmenopausal women reported symptom relief, often within 2 days to 8 weeks, with many noticing improvements around 21 days.*

These symptom changes occurred during the same study period in which women also showed shifts in key hormonal markers, demonstrating broader support for overall well-being.*

Women in the studies commonly reported:

  • Relief from symptoms such as hot flashes, night sweats and disrupted sleep*
  • More stable mood and emotional well-being*
  • Improved energy and day-to-day vitality*
  • A clear effect demonstrated through placebo crossover design: women improved on Femmenessence, worsened on placebo, and improved again when switched back.*
  • 95% success rate when women were supported by our Medical Team during real-world use*

Publication:

Estradiol

In published double-blind, placebo-controlled clinical trials on postmenopausal women, those taking Femmenessence® MacaPause® experienced a statistically significant increase in estradiol—over 200% on average in just two months—compared to placebo.*

This hormonal shift occurred during the same study period in which women also reported improvements in menopausal symptoms, as measured separately using validated symptom scales.*

Women commonly reported:

  • Fewer hot flashes and night sweats*
  • More stable mood and energy levels*
  • Improved sleep quality and reduced fatigue*
  • Support for overall well-being and vitality*

By supporting the body’s natural ability to regulate estradiol—rather than adding hormones—Femmenessence® MacaPause® helps support healthier hormonal communication during postmenopause.*

Publication:

FSH

As women move into postmenopause, FSH levels increase significantly as the ovaries shift away from producing reproductive hormones.

In published double-blind, placebo-controlled clinical trials, postmenopausal women taking Femmenessence® MacaPause® experienced a statistically significant decrease in FSH—an average reduction of 34% within four months—compared to placebo.*

This hormonal shift occurred during the same study period in which women also reported improvements in menopausal symptoms, as measured separately using validated symptom scales.*

Women commonly reported:

  • Fewer hot flashes and night sweats*
  • More consistent energy and steadier mood*
  • Improved sleep and overall well-being*

By supporting the body’s natural ability to regulate FSH—rather than adding hormones—Femmenessence® MacaPause® helps support healthier hormonal communication during postmenopause.*

Publication:

Heart Health

After menopause, natural declines in estrogen can affect how the body regulates lipids such as HDL, LDL and triglycerides, as well as factors like blood pressure and weight. These shifts can influence overall cardiovascular markers, which in turn can affect how women feel day to day.

In published double-blind, placebo-controlled clinical trials, postmenopausal women taking Femmenessence® MacaPause® showed statistically significant improvements in several key cardiovascular markers, including*:

  • HDL (“good”) cholesterol*
  • LDL (“bad”) cholesterol*
  • Triglycerides*
  • Blood pressure and body weight*

These improvements occurred during the same study period in which women also reported benefits in energy, mood and overall well-being measured separately through validated symptom scales.*

By supporting healthy hormonal communication and overall physiological balance, Femmenessence MacaPause® helps support the systems that influence circulation and day-to-day vitality during postmenopause.*

Publication: 

Bone Health

After menopause, natural declines in estradiol can accelerate changes in bone density, influencing long-term skeletal health. In the MacaPause clinical trials, researchers evaluated whether supporting healthier hormonal balance could also influence bone density markers.

In a published, double-blind, placebo-controlled pilot study, postmenopausal women taking Femmenessence® MacaPause® showed positive changes in bone density markers—including improvements in total bone density and Z-scores—compared with placebo over 4 months.*

These findings reflect early evidence of broader physiological support observed during the same research period, when women also experienced improvements in hormone patterns and menopausal symptoms.*

Women in the study commonly showed:

  • Higher total bone density after four months on Femmenessence®*
  • Increased Z-scores compared to baseline*
  • Trends not observed in the placebo group

By supporting the body’s natural hormonal communication network, Femmenessence helps maintain the internal balance that influences bone health during postmenopause—supporting strength for the years ahead.*

Publication: 

Mood, Focus & Emotional Well-Being

During postmenopause, natural changes in hormone levels can influence how women feel emotionally and mentally. Many women experience shifts in mood, energy, sleep patterns and overall sense of well-being during this stage.

In published double-blind, placebo-controlled clinical trials, postmenopausal women taking Femmenessence® MacaPause® reported statistically significant improvements in mood, energy and emotional well-being compared to placebo, as measured through validated symptom scales.*

These improvements occurred during the same study period in which women also experienced changes in other markers of menopausal health, showing a broader shift in day-to-day well-being.*

Women commonly reported:

  • Improved mood and emotional steadiness*
  • Better energy and overall vitality*
  • More restful sleep and reduced nervousness*

Femmenessence® MacaPause® contains a natural spectrum of amino acids and plant compounds—including macamides and macaenes—which support overall well-being and help maintain healthy communication throughout the body.*

Publication: 

Hair, Skin & Nail Health

During postmenopause, natural declines in estradiol can affect hydration, elasticity, and the appearance of hair, skin and nails. Many women notice changes such as dryness, thinning or reduced vitality during this stage.

In published double-blind, placebo-controlled clinical trials, postmenopausal women taking Femmenessence® MacaPause® reported visible improvements in hair thickness, skin vitality and nail strength after four months, compared to placebo.*

These appearance-related improvements occurred during the same study period in which women also reported benefits in mood, energy and overall well-being, as measured separately using validated symptom scales.*

Women in the study commonly reported:

  • Healthier-looking skin with improved vitality*
  • Stronger nails*
  • Thicker-feeling or more resilient hair*

By supporting the body’s natural hormonal communication, Femmenessence MacaPause® helps maintain the internal balance that contributes to visible vitality during postmenopause.*

Publication: 

Case Report: Surgical Menopause

Surgical menopause occurs when the ovaries are removed—a procedure known as oophorectomy—resulting in an abrupt drop in hormones. This sudden change can lead to experiences such as hot flashes, night sweats, sleep disruption and emotional challenges.

While double-blind, placebo-controlled trials demonstrate that Femmenessence® MacaPause® supports groups of postmenopausal women, case reports offer insight into how individuals may experience its use during more complex or rapid transitions.

One published case described a 32-year-old woman who entered immediate menopause after hysterectomy and oophorectomy. She reported symptoms including hot flashes, night sweats, anxiousness, sleep disruption and mood fluctuations—commonly associated with surgical menopause.

Her care plan included:

  • Femmenessence® MacaPause®
  • A tailored nutrition plan
  • Nutrient supplementation
  • Lifestyle and wellness recommendations

Over eight weeks, she reported noticeable improvements in several of her symptoms, including fewer hot flashes, steadier mood and more restful sleep, as documented in the case report.*

It’s important to note that case reports describe the experience of a single individual and are not intended to predict outcomes for others. However, they offer meaningful context for understanding real-world use alongside clinical trial findings.*

The woman in this case report noted:

  • Fewer hot flashes and night sweats*
  • Improved sleep quality*
  • More stable mood and emotional well-being*
  • Support as part of a non-hormonal wellness approach*

Publication:

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

USDA Organic Vegan Kosher 3rd-Party Tested Gluten, Soy, Dairy, Allergen-Free No Fillers, Additives, Preservative

INGREDIENTS AND SOURCING

Femmenessence: Where Science Meets Intention

Every step of Femmenessence®—from the soil where our maca is grown to create Maca-GO® to the science that validates our formulation—is guided by one purpose: to support women’s hormonal health naturally and effectively. Rooted in integrity and backed by clinical research, this is where nature’s intelligence and human intention come together to create a real, measurable difference.

Life-Stage-Specific Proprietary Formulation

Not all maca is the same. There are 17 distinct types–called phenotypes–with different DNA, nutrient profiles and physiological effects. Maca-GO®, a proprietary combination of phenotypes used in Femmenessence® MacaPause®, is formulated in precise ratios for postmenopausal women.

Tested in Published Human Clinical Trials

Developed after more than a decade of research, Femmenessence® is one of the few natural products with double-blind, placebo-controlled human clinical trials published in respected medical journals. In postmenopausal women, these trials showed statistically significant changes in key hormone markers, along with improvements in symptoms and overall well-being.*

Trusted by the World’s Leading Experts in Women’s Health

For more than 18 years, health practitioners around the world have recommended Femmenessence® to their patients, recognizing its scientific credibility and clinical support for hormonal balance.*

Vertical Integration: Ensuring Quality from Seed to Soul

We oversee every step of the journey—from high-altitude farming to formulation, research and final packaging. This vertical integration helps ensure purity, potency and consistency in every capsule, upholding our commitment to supporting women’s health at every stage.*

Not All Maca Is Created Equal

Why Our Maca Is Different

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For centuries, maca has been known in the Andes as a sacred root—cultivated where intense sun, thin air and freezing nights shaped a plant unlike any other. Used by Indigenous communities for more than 2,000 years, maca was valued for nourishment, vitality and resilience.

But not all maca is the same. There are 17 distinct types—called phenotypes—that differ in DNA, color and active compounds, producing different effects on the body. Most maca on the market combines these types randomly, which can make them ineffective or even worsen symptoms.*

Femmenessence® MacaPause® contains Maca-GO®—a proprietary, life-stage-specific combination of phenotypes developed by Symphony Natural Health after more than a decade of research.

Femmenessence® is the only formulation with published, double-blind, placebo-controlled clinical trials demonstrating statistically significant effects on key hormones in postmenopausal and perimenopausal women.

Every maca phenotype contains a unique profile of amino acids, vitamins and minerals that support hormone-producing glands.

Femmenessence® delivers a full amino acid profile—the essential building blocks for hormones and neurotransmitters—with a nutrient density that exceeds that of leading maca extracts in both the U.S. and Europe.*

The chart below shows a comparative amino acid chromatogram of Femmenessence [1 & 6] vs. other leading maca extracts [3 & 4].


Why Our Maca Is Different

From the Andes: Where It’s Grown & Why It Matters

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True maca grows only at extreme altitudes, between 11,500 and 16,400 feet in the central highlands of Peru. The harsh conditions and mineral-rich volcanic soil allow the plant to develop its full spectrum of bioactive compounds.

We partner directly with local farming communities, honoring traditional organic practices that preserve both the land and cultural heritage:

  • Crops are rotated every 5–7 years.
  • Roots are hand-harvested and sun-dried at altitude.
  • No chemical fertilizers or solvents are ever used.

This commitment sustains the potency of our raw materials and the integrity of the communities that cultivate them.

Precision Processing: From Roots to Results

+

The maca used to create Maca-GO® undergoes a proprietary, solvent-free process that uses only water, temperature and pressure—never chemicals—to concentrate and stabilize the active ingredients.

This process optimizes bioavailability (up to 99%), allowing the body to utilize beneficial compounds efficiently.

Each batch is standardized for potency and consistency—so every capsule delivers the same profile studied in our clinical trials.*

Glucosinolates—compounds also found in cruciferous vegetables—play a critical role in hormone metabolism and detoxification. They’re sensitive to heat and oxidation, which is why our solvent-free process is so important. Femmenessence® preserves high levels of glucosinolates—up to 400x those found in broccoli and Brussels sprouts—maintaining the bioactive compounds your body needs for hormonal communication and balance.

The chart below compares glucosinolate concentrations in Femmenessence with those in other maca extracts.

Precision Processing: From Roots to Results

Purity You Can Trust

+

Every capsule of Femmenessence® MacaPause® is:

  • USDA Organic, Non-GMO, and Vegan
  • Free from fillers, preservatives, gluten, soy, dairy and corn
  • Third-party tested for heavy metals, purity and safety

From soil to supplement, we uphold the highest standards to ensure purity, potency and transparency—because integrity is part of every step we take.

Clinically Studied. Practitioner Trusted.

+

Unlike many natural products that rely on generic ingredient research, Femmenessence® MacaPause® is the exact formulation used in published, double-blind, placebo-controlled human clinical trials.

Our double-blind, placebo-controlled human clinical trials have been published in respected international medical journals and presented to leading organizations, including the North American Menopause Society (NAMS) and the American College of Obstetricians and Gynecologists (ACOG).

That’s why Femmenessence® is trusted by physicians, naturopaths and integrative health experts around the world.

The Symphony Natural Health Difference

+

We call our approach Seed to Soul. We don’t just cultivate the maca used to create our formulations—we research it, transform it, standardize it and verify every batch.

By overseeing each stage from cultivation to packaging, we ensure unmatched purity, potency and consistency, from the highlands of Peru to your hands.

All to support women’s hormonal health and whole-person well-being—physical, emotional, mental and spiritual.

Available at these grocers and wellness centers

From our Community

Customer Reviews

  • Healthcare Provider

    "To me, health is more than the absence of disease. It’s the vibrant spectrum of physical, emotional, mental, and spiritual aspects that work together like a symphony. Femmenessence allows for this whole-self integration by nourishing the endocrine system. As I go through the journey of perimenopause, I am grateful to be able to bring in the innate wisdom of plants to naturally allow my own inner wisdom to express!"

    Dr. Deanna Minich PhD, CNS, FACN, IFMCP

  • Healthcare Provider

    "I have used Femmenessence for 8 years in my women's health practice. It has become a mainstay botanical approach for my peri- and postmenopausal patients. I also often use Femmenessence for added heart and bone health support. I am a big advocate of Femmenessence, as it has given me a tool I didn't have to help me, help more women.*"

    Kathryn Landherr M.D., OB/GYN

  • Healthcare Provider

    "Before I recommend hormones or herbs, I begin the process of supporting a patient’s hormonal balance with Femmenessence. In conjunction with lifestyle modification, this plant-based intervention serves to re-educate the complex feedback loops between her brain and endocrine system. In this way, we are leveraging the power of natural medicine to heal. In 6 years of clinical use of this product, the results, within two cycles, remain astounding."

    Kelly Brogan M.D.

  • Healthcare Provider

    "It’s not often that a natural products company has the level of commitment to research that I see from Symphony Natural Health. Their double blind, randomized trials on Femmenessence in early postmenopausal women showed not only significant symptom relief, but the impact on serum estradiol and FSH levels, and even an influence on markers of bone turnover. The implications for women's health are considerable and I have experienced positive results with my patients."

    Tori Hudson N.D.

  • Healthcare Provider

    "It’s a rare occurrence in medicine when you can find a non-prescription supplement that helps women to the point where it becomes one of your primary go-to’s for hormone health. I have wholeheartedly endorsed Femmenessence® for the past 6 years, not just because of their mission statement and desire to help women, but also because of the research, time, care, foundations and scientific evidence they’ve invested in improving women’s health. I highly encourage every one of my patients, whether they’re pre-menopausal or menopausal or even those with PMS, irregular periods, and other hormonal imbalances, to try Femmenessence."

    Shawn Tassone M.D., OB/GYN
Frequently Asked Questions

Questions About MacaPause® 3-Box Subscription?
We’re Here to Help

How is Femmenessence® MacaPause® different from other menopause supplements?

+

Most menopause supplements either add hormones (synthetic, bioidentical, or plant estrogens) or rely on generic maca powders that haven’t been clinically studied in postmenopausal women.

Femmenessence is different.

Femmenessence is the first natural product with published double-blind, placebo-controlled human clinical trials showing statistically significant changes in key hormones in peri- and postmenopausal women.*

MacaPause® is formulated specifically for postmenopause, using a life-stage-targeted combination of maca phenotypes designed to support the body’s own hormone production and communication—not add hormones.*

Instead of masking symptoms, Femmenessence works through the endocrine system to support the root cause of hormonal changes that influence hot flashes, night sweats, sleep, mood, energy, and overall well-being.*

This combination of rigorous clinical research, a life-stage-specific formulation, and real-world results sets Femmenessence apart.

How long will it take before I notice results?

+

In published clinical trials, 84% of postmenopausal women reported improvements in symptoms within 2–8 weeks, with many noticing changes around 21 days (one box).*

Every woman’s experience is different. Some feel a shift within days; others may need several weeks as their endocrine system adapts. Factors like hydration, timing of doses, stress, nutrition, and overall health history can influence how quickly the body responds.

Many women continue to experience deeper benefits with consistent use over multiple months, and our Medical Team is always available to help optimize your routine for the best results.*

What symptoms can MacaPause® help support?

+

In published clinical trials, postmenopausal women taking Femmenessence® MacaPause® reported support for:*

  • Hot flashes & night sweats*
  • Sleep quality*
  • Mood & emotional well-being*
  • Daily energy & vitality*
  • Mental clarity*

Clinical research also showed statistically significant support for key hormone markers such as estradiol and FSH, along with benefits related to heart health, bone health, and overall well-being.*

Is MacaPause® safe to take with other medications?

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In most cases, Femmenessence® can be taken alongside supplements or over-the-counter medications. We recommend taking MacaPause® at least one hour apart from other products to support optimal absorption.

Every woman’s health history is unique, so it’s always best to consult your healthcare provider before beginning any new supplement.

As a precaution, Femmenessence should not be used with:

  • Tamoxifen
  • Hormone-suppressing medications

If you have specific questions about combining Femmenessence with your current routine, our Medical Team is available to help provide personalized guidance.*

Do I need to take MacaPause® forever?

+

Not necessarily. Many women take the full serving for 6–9 months and then shift to a maintenance dose for continued hormonal support.

Because postmenopause is an ongoing stage of life, some women choose to continue long-term to support symptom relief, emotional steadiness, heart health, and whole-body well-being.*

Others take breaks or adjust their routine over time. Your needs may change, and our Medical Team is here to help you determine the best long-term plan for your goals.*

What makes MacaPause® clinically proven?

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Unlike supplements that borrow claims from individual ingredients, Femmenessence® MacaPause® is the exact formulation tested in multiple published double-blind, placebo-controlled human clinical trials.

These studies were conducted specifically in postmenopausal women, and results have been published in respected international medical journals. Research showed statistically significant support for key hormone markers—such as estradiol and FSH—as well as meaningful improvements in symptom scores, heart health markers, bone health markers, and overall well-being.*

This level of clinical validation is rare in the natural hormone-support category and is one of the reasons Femmenessence® is trusted by practitioners worldwide.*

How do I take MacaPause®?

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The standard serving is 2 capsules, twice daily with 8–16 oz. of water, taken before or between meals.

  • Take your first serving in the morning
  • Take your second serving in the afternoon, ideally 30 minutes before your usual low-energy time

Not to be taken in conjunction with hormone-suppressing medications such as Tamoxifen.

Please consult your healthcare professional before starting Femmenessence if you are taking any medications.

Our Medical Team is available if you need support personalizing your routine.*

What if MacaPause® doesn’t work for me?

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Every woman’s experience in postmenopause is unique. Some notice changes quickly, while others need more time as their endocrine system adapts.

If you’re not seeing the results you expected, our Medical Team can help personalize your routine — adjusting timing, hydration, dosage approach, or supporting lifestyle factors can make a meaningful difference.

In clinical practice, women who work with our Medical Team have achieved success rates up to 95% by tailoring their plan and supporting the body’s natural hormonal communication.*

We’re here to help you find what works best for your body.

Will Femmenessence MacaPause upset my digestive system?

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Digestive discomfort is uncommon, but because hormone communication influences many systems in the body, some women may notice temporary changes as they begin MacaPause®.

If you experience mild digestive symptoms, here are a few helpful adjustments:

  • Reduce your serving size by half until symptoms ease
  • Take MacaPause® with food for the first 7–10 days, then shift to taking it between meals
  • Add a probiotic to support overall digestive health
  • Incorporate Sole therapy to support hydration and GI absorption

Most women find that these simple changes help their bodies adjust quickly. If you have questions or need personalized guidance, our Medical Team is always here to help.*

OUR MEDICAL TEAM

World-Class Leaders in Women's Health—Here For You

Our medical team is different. With over 200 years of combined clinical experience—treating more than 150,000 women just like you—they're the experts other doctors turn to for continuing education and guidance. At Symphony Natural Health, they're not just figureheads. They create trusted health resources and provide personal support seven days a week. Most importantly, they're your partners in health—bringing the expertise, compassion and guidance you can count on every step of the way.

Jan Roberts

Jan Roberts

Pharmacist & Clinical Nutritionist

Dr. Mona Fahoum

Dr. Mona Fahoum

Naturopathic Doctor

Dr. Wendy Warner

Dr. Wendy Warner

MD & OBGYN

Dr. Deanna Minich

Dr. Deanna Minich

Ph.D

Dr. Tori Hudson

Dr. Tori Hudson

Naturopathic Doctor

Dr. Kim Ross

Dr. Kim Ross

Doctor in Clinical Nutrition

Dr. Corey Schuler

Dr. Corey Schuler

Nurse Practitioner & D.C.

Dr. Marc Sklar

Dr. Marc Sklar

L.Ac & Fertility Expert

Jan Roberts

Jan Roberts

Pharmacist & Clinical Nutritionist

Dr. Mona Fahoum

Dr. Mona Fahoum

Naturopathic Doctor

Dr. Wendy Warner

Dr. Wendy Warner

MD & OBGYN

Dr. Deanna Minich

Dr. Deanna Minich

Ph.D

Dr. Tori Hudson

Dr. Tori Hudson

Naturopathic Doctor

Dr. Kim Ross

Dr. Kim Ross

Doctor in Clinical Nutrition

Dr. Corey Schuler

Dr. Corey Schuler

Nurse Practitioner & D.C.

Dr. Marc Sklar

Dr. Marc Sklar

L.Ac & Fertility Expert

Learn More About Our Medical Team
FROM HORMONAL HEALTH TO WHOLE HEALTH

Postmenopause Health Hub

Most health content is one-size-fits-all. Ours isn’t. Here you’ll find life-stage-specific content created and curated by our medical team for your postmenopause health. More than articles, this is a space for trusted answers, expert insights and whole-health support on topics from night sweats and bone and heart health to intimacy and more—so you can feel informed, connected and cared for at every stage.

POSTMENOPAUSE HEALTH RESOURCES

Menopause Redefined: A Holistic Approach to Hormones and Wellness

BLOG — JAN ROBERTS

Read Now

The Whole Health Guide to Bone Health

GUIDE — THE MEDICAL TEAM

Download Now

Find Hormonal Harmony Naturally

BLOG - SYMPHONY NATURAL HEALTH MEDICAL TEAM

Read Now
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Beyond Hormone Balance: Support for the Whole You

Your journey doesn’t stop at hormonal balance—it begins there. These Symphony Natural Health products were carefully selected to complement Femmenessence®—supporting restful sleep, gentle detoxification and healthy hydration, three areas often affected by hormonal shifts. Together, they help restore balance where your body needs it most—so you can feel rested, replenished and re-energized every day.*

Herbatonin® 0.3 mg

Hormonal shifts can disrupt more than balance–they can affect sleep, recovery and energy.

Herbatonin® 0.3 mg is the world’s first phyto-melatonin–a 100% plant-based extract from alfalfa, chlorella and rice that supports natural circadian rhythm, antioxidant protection and cellular health.*

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pH Quintessence

Hormonal changes can make it harder for your body to stay balanced.


pH Quintessence is a 40:1 Alfalfa concentrate rich in chlorophyll, antioxidants, vitamins, minerals and essential amino acids, that helps alkalize the body by balancing pH and supporting detox and the metabolism of hormones.*

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pH Quintessence

Detoxification Support

Sole Jar Plus Stones product glass jar filled with water and Himalayan Crystal Salt stones with cork cover and tan product box both featuring Himalayan Crystal Salt logo, and wooden spoon, on white background

Hydration isn’t just about drinking more water—it’s about how well your cells absorb it. 

Sole, a mineral-rich Himalayan salt solution, helps support hydration, an essential foundation for hormone balance and overall health.* 

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Original Himalayan Crystal Salt®

Sole Jar Plus Stones

JOIn THE FEMMENESSENCE COMMUNITY

Follow us @Femmenessence

JOIN THE MOVEMENT

Bringing Feminine Consciousness To Balance in

For too long, society has moved out of balance—elevating the masculine while neglecting the feminine. The Femmenessence Movement seeks to restore balance by honoring the feminine consciousness within us all, creating a society that is more connected, compassionate, and caring. Beyond health, it’s about reshaping how we lead, learn and live—to create a brighter now and a more balanced future for generations to come.

Thank you for joining our movement!